Evidence map›Paper›PMID 36539740›Full record

ReviewBMC neurology2022

The pathogenesis and treatment of posterior reversible encephalopathy syndrome after neuromyelitis optica spectrum disorder: a case report and literature review.

Bo Yang, Lei Guo, Xu Yang, Nengwei Yu

Open access · goldAbstract readReviewCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Review in BMC neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Uncommon Non-MS Demyelinating Disorders of the Central Nervous System.Current neurology and neuroscience reports · 2025
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Bo YangDepartment of Center for Psychosomatic Medicine, Sichuan Provincial Center for Mental Health,Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Lei GuoDepartment of Neurosurgery, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Xu YangDepartment of Encephalopathy, Traditional Chinese Medicine Hospital of Leshan, Leshan, China.
Nengwei YuDepartment of Neurology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China. 18981838652@126.com.
University of Electronic Science and Technology of China · CN

Funding

Major science and technology application demonstrat- ion project of Chengdu Science and Technology Bureau, Sichuan Province 2019-YF09-00142-SN
6 · The paper itself

Abstract

backgroundPosterior reversible encephalopathy syndrome (PRES) is a rare disease characterized by reversible subcortical vasogenic brain edema. Neuromyelitis optica spectrum disorder (NMOSD) is a frequent neurological autoimmune disease that is rarely reported to complicate PRES. CASE PRESENTATION: Here, we report a case of neuromyelitis optica (NMO) concurrent with PRES. A 50-year-old woman presented with severe impairment of her health visual acuity, with significantly worsening of the motor weakness in both lower limbs during methylprednisolone therapy after her diagnosis of NMO. MRI showed new-onset brain edematous lesions of the bilateral frontal, occipital, and parietal lobes. PRES was considered. Her vision impairment and weakness of the extremities were alleviated after antihypertensive treatment and dehydration. The edema lesions detected by MRI also completely disappeared.

conclusionsWe reviewed 14 cases of NMO with PRES and concluded that the etiology of NMOSD concurrent PRES may be multifactorial, involving pathogenic IgGs against aquaporin-4 (AQP-4) and immunotherapy treatment. Different underlying pathogeneses require different treatment approaches.

Indexed as

Brain EdemaNeuromyelitis OpticaPosterior Leukoencephalopathy SyndromeAquaporin 4FemaleHumansMagnetic Resonance ImagingMiddle AgedAquaporin 4Aquaporin-4ImmunotherapyNeuromyelitis optica spectrum disorderPosterior reversible encephalopathy syndrome

Identifiers

PMID36539740
PMCPMC9764726
OpenAlexW4312114685

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.