Evidence map›Paper›PMID 36539601›Full record

ArticleEye (London, England)2023

National survey of corneal cross-linking (CXL) practice patterns in the United Kingdom during 2019.

Sally Hayes, Philip Jaycock, Nicholas Rees, Francisco C Figueiredo, David P S O'Brart, Keith M Meek

Abstract read
In one paragraph

Article in Eye (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. [Keratoconus progression assessment].Die Ophthalmologie · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sally HayesStructural Biophysics Research Group, School of Optometry and Vision Sciences, Cardiff University, Maindy Road, Cardiff, CF24 4HQ, UK. hayess5@cardiff.ac.uk.
Philip JaycockNuffield Health Bristol Hospital, 3 Clifton Hill, Clifton, Bristol, BS8 1BN, UK.
Nicholas ReesBristol Medical School, University of Bristol, 5 Tyndall Avenue, Bristol, BS8 1UD, UK.ORCID 0000-0002-8197-8849
Francisco C FigueiredoDepartment of Ophthalmology, Royal Victoria Infirmary, Newcastle upon Tyne Hospitals NHS Foundation Trust, Queen Victoria Road, Newcastle upon Tyne, NE1 4LP, UK.ORCID 0000-0002-5876-288X
David P S O'BrartStructural Biophysics Research Group, School of Optometry and Vision Sciences, Cardiff University, Maindy Road, Cardiff, CF24 4HQ, UK.ORCID 0000-0002-1065-3166
Keith M MeekStructural Biophysics Research Group, School of Optometry and Vision Sciences, Cardiff University, Maindy Road, Cardiff, CF24 4HQ, UK.

Funding

Medical Research Council G0900879Medical Research Council MR/S035826/1Medical Research Council MR/S037829/1
6 · The paper itself

Abstract

objectiveTo provide an insight into trends in corneal cross-linking (CXL) practice in the UK, including criteria for progression of corneal ectasia, identification of patients for CXL, the CXL procedure itself and post-operative management.

methodsAll ophthalmologist members of the UK Cross-linking (UK-CXL) Consortium were invited to complete an online survey about CXL practice for the year 2019. The data collected was anonymised by site and analysed with descriptive statistics.

resultsResponses were received from 16 individual CXL centres (16/38; 42% response rate) and the data represented ~2,000 CXL procedures performed in the UK in 2019. The commonest indication for CXL was progressive keratoconus. Between centres, there were variations in diagnostic evaluation, patient selection for CXL, the CXL procedure and the pre- and post-operative monitoring of patients.

conclusionConsistent with the wide number of CXL treatment techniques described in the published literature world-wide, variations in the monitoring of corneal ectasia, indications for CXL, CXL practice and post-CXL follow-up were found to exist between UK-based CXL centres.

Indexed as

KeratoconusPhotochemotherapyCollagenCorneal Cross-LinkingCorneal TopographyCross-Linking ReagentsDilatation, PathologicHumansPhotosensitizing AgentsRiboflavinUltraviolet RaysUnited KingdomCollagenCross-Linking ReagentsPhotosensitizing AgentsRiboflavin

Identifiers

PMID36539601
PMCPMC9767393

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.