ArticleJournal of medical entomology2023
Evidence of Permethrin Resistance and Fipronil Tolerance in Rhipicephalus sanguineus s.l. (Acari: Ixodidae) Populations From Florida and California.
Article in Journal of medical entomology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
11 citing papers in PubMed, 25 citations in OpenAlex.
- Synergistic activity of carvacrol in combination with permethrin against permethrin resistant Rhipicephalus annulatus.Scientific reports · 2026Article
- Control ofInfectious Disease Modelling · 2025Article
- Detection of coumaphos, fipronil, flumethrin and amitraz susceptibility in Rhipicephalus sanguineus s.l. (Acari: Ixodidae) from Mexico.Veterinary research communications · 2025Article
- First report of VGSC mutations for resistance to synthetic pyrethroids in brown dog ticks (Rhipicephalus sanguineus sensu stricto) from Brazil.Parasites & vectors · 2025Article
- Mutations in the voltage-gated sodium channel associated with permethrin resistance in Rhipicephalus linnaei populations in Thailand.Scientific reports · 2025Article
- The Rhipicephalus sanguineus group: updated list of species, geographical distribution, and vector competence.Parasites & vectors · 2024Review
- A rapid tick exposure test for monitoring acaricide resistance in Rhipicephalus sanguineus sensu lato ticks on dogs.Parasites & vectors · 2024Article
- Repellent activity of essential oils to the Lone Star tick, Amblyomma americanum.Parasites & vectors · 2024Article
- Exploring the Larvicidal and Repellent Potential of Taurus Cedar (Molecules (Basel, Switzerland) · 2023Article
- Susceptibility ofPathogens (Basel, Switzerland) · 2023Article
- Detection of ivermectin and fipronil resistance inVeterinary world · 2023Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Rhipicephalus sanguineus s.l. (Latreille), is a vector of multiple disease-causing pathogens to humans and dogs. Permethrin and fipronil are two acaricides used to manage R. sanguineus s.l. infestations. Homeowners have reported treatment failures in managing brown dog ticks using permethrin and fipronil based products. Previous studies demonstrated that high permethrin resistance in some R. sanguineus s.l. populations was due to metabolic detoxification and target site insensitivity. In this study, three R. sanguineus s.l. strains, one from a laboratory colony (NC) and two colonies originally collected from Florida (FL) and California (CA), were evaluated for resistance expression against permethrin and fipronil. Metabolic detoxification mechanisms were evaluated in the FL strain using three synergists, while a polymerase chain reaction assay was used to detect a resistance mutation in all strains. The NC strain was susceptible to both permethrin and fipronil, while both the FL and CA strains exhibited high resistance to permethrin and tolerance to fipronil. The synergist tests and PCR results indicated that the FL strain utilized both metabolic resistance and target site insensitivity against permethrin, while the CA strain was documented to have the target-site insensitivity resistant allele. This study confirmed permethrin resistance in both California and Florida populations and its persistence in Florida populations, although its susceptibility can potentially be increased by adding a synergist. Fipronil resistance was not detected suggesting this acaricide may provide suitable tick control.
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Registered trials
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