Evidence map›Paper›PMID 36539174›Full record

ArticleArchives of physical medicine and rehabilitation2023

AMPREDICT PROsthetics-Predicting Prosthesis Mobility to Aid in Prosthetic Prescription and Rehabilitation Planning.

Daniel C Norvell, Mary Lou Thompson, Aaron Baraff, Wayne T Biggs, Alison W Henderson, Kathryn P Moore, Aaron P Turner, Rhonda Williams, Charles C Maynard, Joseph M Czerniecki

Abstract read
In one paragraph

Article in Archives of physical medicine and rehabilitation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. AMPREDICT Mobility-4: A Novel Four Category Mobility Outcome Prediction Model for Patients Undergoing Vascular Amputation.European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery · 2025
    Article
  3. AMPREDICT MoRe: Predicting Mortality and Re-amputation Risk after Dysvascular Amputation.European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Daniel C NorvellVA Puget Sound Health Care System, Seattle, WA; Department of Rehabilitation Medicine, University of Washington, Seattle, WA; VA Center for Limb Loss and Mobility (CLiMB), Seattle, WA. Electronic address: daniel.norvell@va.gov.
Mary Lou ThompsonDepartment of Biostatistics, University of Washington, Hans Rosling Center for Population Health, Seattle, WA.
Aaron BaraffVA Puget Sound Health Care System, Seattle, WA; Seattle Epidemiologic Research and Information Center (ERIC), Seattle, WA.
Wayne T BiggsVA Puget Sound Health Care System, Seattle, WA.
Alison W HendersonVA Puget Sound Health Care System, Seattle, WA; VA Center for Limb Loss and Mobility (CLiMB), Seattle, WA.
Kathryn P MooreVA Puget Sound Health Care System, Seattle, WA; Seattle Epidemiologic Research and Information Center (ERIC), Seattle, WA.
Aaron P TurnerVA Puget Sound Health Care System, Seattle, WA; Department of Rehabilitation Medicine, University of Washington, Seattle, WA; VA Center for Limb Loss and Mobility (CLiMB), Seattle, WA.
Rhonda WilliamsVA Puget Sound Health Care System, Seattle, WA; Department of Rehabilitation Medicine, University of Washington, Seattle, WA; VA Center for Limb Loss and Mobility (CLiMB), Seattle, WA.
Charles C MaynardVA Puget Sound Health Care System, Seattle, WA.
Joseph M CzernieckiVA Puget Sound Health Care System, Seattle, WA; Department of Rehabilitation Medicine, University of Washington, Seattle, WA; VA Center for Limb Loss and Mobility (CLiMB), Seattle, WA.

Funding

AMPREDICT PRO- Predicting Prosthetic Mobility and Matching Prosthetic Characteristics to Patient Functional GoalsI01RX002919 · VA · VA PUGET SOUND HEALTHCARE SYSTEM · PI NORVELL, DANIEL C · 2019 to 2021
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RRD VA I01 RX002919
6 · The paper itself

Abstract

objectiveTo develop and validate a patient-specific multivariable prediction model that uses variables readily available in the electronic medical record to predict 12-month mobility at the time of initial post-amputation prosthetic prescription. The prediction model is designed for patients who have undergone their initial transtibial (TT) or transfemoral (TF) amputation because of complications of diabetes and/or peripheral artery disease.

designMulti-methodology cohort study that identified patients retrospectively through a large Veteran's Affairs (VA) dataset then prospectively collected their patient-reported mobility.

settingThe VA Corporate Data Warehouse, the National Prosthetics Patient Database, participant mailings, and phone calls.

participantsThree-hundred fifty-seven veterans who underwent an incident dysvascular TT or TF amputation and received a qualifying lower limb prosthesis between March 1, 2018, and November 30, 2020 (N=357).

interventionsNot applicable.

main outcome measureThe Amputee Single Item Mobility Measure (AMPSIMM) was divided into a 4-category outcome to predict wheelchair mobility (0-2), and household (3), basic community (4), or advanced community ambulation (5-6).

resultsMultinomial logistic lasso regression, a machine learning methodology designed to select variables that most contribute to prediction while controlling for overfitting, led to a final model including 23 predictors of the 4-category AMPSIMM outcome that effectively discriminates household ambulation from basic community ambulation and from advanced community ambulation-levels of key clinical importance when estimating future prosthetic demands. The overall model performance was modest as it did not discriminate wheelchair from household mobility as effectively.

conclusionsThe AMPREDICT PROsthetics model can assist providers in estimating individual patients' future mobility at the time of prosthetic prescription, thereby aiding in the formulation of appropriate mobility goals, as well as facilitating the prescription of a prosthetic device that is most appropriate for anticipated functional goals.

Indexed as

AmputeesArtificial LimbsAmputation, SurgicalCohort StudiesHumansLower ExtremityPrescriptionsRetrospective StudiesAmputationLower extremityPeripheral artery diseaseProsthesisRehabilitation

Identifiers

PMID36539174
PMCPMC10073310

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.