Evidence map›Paper›PMID 36538549›Full record

ArticlePloS one2022

Optimising reporting of adverse events following immunisation by healthcare workers in Ghana: A qualitative study in four regions.

Raymond Akawire Aborigo, Paul Welaga, Abraham Oduro, Anna Shaum, Joseph Opare, Alex Dodoo, Hilda Ampadu, Jane F Gidudu

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Raymond Akawire AborigoNavrongo Health Research Centre, Research and Development Division, Ghana Health Service, Navrongo, Ghana.ORCID 0000-0003-0642-9265
Paul WelagaNavrongo Health Research Centre, Research and Development Division, Ghana Health Service, Navrongo, Ghana.
Abraham OduroNavrongo Health Research Centre, Research and Development Division, Ghana Health Service, Navrongo, Ghana.
Anna ShaumCenter for Global Health, Global Immunisation Division, Centers for Disease Control and Prevention, Atlanta, GA, United States of America.ORCID 0000-0001-7088-5754
Joseph OpareThe Ghana Second Year of Life Vaccine Platform (2YL), Accra, Ghana.
Alex DodooThe African Collaborating Centre for Pharmacovigilance, Accra, Ghana.
Hilda AmpaduThe African Collaborating Centre for Pharmacovigilance, Accra, Ghana.
Jane F GiduduCenter for Global Health, Global Immunisation Division, Centers for Disease Control and Prevention, Atlanta, GA, United States of America.
Navrongo Health Research Centre · GHCenters for Disease Control and Prevention · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDespite the emphasis on reporting of Adverse Events Following Immunisation (AEFIs) during didactic training sessions, especially prior to new vaccine introductions, it remains low in Ghana. We explored the factors underlying the under-reporting of AEFI by healthcare workers (HCWs) to provide guidance on appropriate interventions to increase reporting.

methodsWe conducted an exploratory descriptive in-depth study of the factors contributing to low reporting of AEFI among HCWs in four regions in Ghana. Key informant interviews (KII) were held with purposively selected individuals that are relevant to the AEFI reporting process at the district, regional, and national levels. We used KII guides to conduct in-depth interviews and used NVivo 10 qualitative software to analyse the data. Themes on factors influencing AEFI reporting were derived inductively from the data, and illustrative quotes from respondents were used to support the narratives.

resultsWe conducted 116 KIIs with the health managers, regulators and frontline HCWs and found that lack of information on reportable AEFIs and reporting structures, misunderstanding of reportable AEFIs, heavy workload, cost of reporting AEFIs, fear of blame by supervisors, lack of motivation, and inadequate feedback as factors responsible for underreporting of AEFIs. Respondents suggested that capacity building for frontline HCWs, effective supervision, the provision of motivation and feedback, simplification of reporting procedures, incentives for integrating AEFI reporting into routine monitoring and reporting, standardization of reporting procedures across regions, and developing appropriate interventions to address the fear of personal consequences would help improve AEFI reporting.

conclusionFrom the perspectives of a broad range of key informants at all levels of the vaccine safety system, we found multiple factors (both structural and behavioural), that may impact HCW reporting of AEFI in Ghana. Improvements in line with the suggestions are necessary for increased AEFI reporting in Ghana.

Indexed as

Adverse Drug Reaction Reporting SystemsVaccinationVaccinesGhanaHealth PersonnelHumansVaccines

Identifiers

PMID36538549
PMCPMC9767370
OpenAlexW4312003281

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.