Evidence map›Paper›PMID 36538202›Full record

ArticleThe protein journal2023

Inhibitory Action of Omega-3 and Omega-6 Fatty Acids Alpha-Linolenic, Arachidonic and Linoleic acid on Human Erythrocyte Acetylcholinesterase.

Mehmet Berk Akay, Kübra Şener, Suat Sari, Ebru Bodur

Abstract read
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In one paragraph

Article in The protein journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Microwave-Assisted Extraction ofJournal of fungi (Basel, Switzerland) · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mehmet Berk AkayFaculty of Medicine, Department of Medical Biochemistry, Hacettepe University, 06100, Ankara, Turkey.ORCID 0000-0001-8595-4062
Kübra ŞenerFaculty of Science, Department of Biology, Gazi University, 06500, Ankara, Turkey.ORCID 0000-0002-8759-9444
Suat SariFaculty of Pharmacy, Department of Pharmaceutical Chemistry, Hacettepe University, 06100, Ankara, Turkey.ORCID 0000-0002-8248-4218
Ebru BodurFaculty of Medicine, Department of Medical Biochemistry, Hacettepe University, 06100, Ankara, Turkey. bodurebru@yahoo.com.ORCID 0000-0001-5829-5487

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acetylcholinesterase (AChE, E.C. 3.1.1.7) termed as the true cholinesterase functions to end cholinergic transmission at synapses. Due to its diverse expression in non-neural tissues such as erythrocytes and bones along with its various molecular forms, researchers seek a non-classical role for this protein. Here, the inhibitory action of unsaturated 18 carbon fatty acids linoleic acid and alpha-linolenic acid and 20 carbon fatty acid arachidonic acid on AChE were investigated. Enzyme activity was measured in kinetic assay method according to Ellman assay utilizing acetylthiocholine. Analysis of the activity data revealed that among the fatty acids examined the IC

Indexed as

AcetylcholinesteraseLinoleic Acidalpha-Linolenic AcidArachidonic AcidsCarbonFatty AcidsFatty Acids, UnsaturatedHumansMolecular Docking SimulationAcetylcholinesterasealpha-Linolenic AcidArachidonic AcidsCarbonFatty AcidsFatty Acids, UnsaturatedLinoleic AcidAcetylcholinesterasearachidonic acidinhibition kineticslinoleic acidlinolenic acidmolecular docking

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.