Evidence map›Paper›PMID 36538180›Full record

ArticleMolecular imaging and biology2023

Measurement of Protein Synthesis Rate in Rat by [

D Bochicchio, L Christie, C B Lawrence, K Herholz, C A Parker, R Hinz, H Boutin

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular imaging and biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

D BochicchioDivision of Neuroscience and Experimental Psychology, Faculty of Biology, Medicine and Health, School of Biological Sciences, University of Manchester, Manchester, M13 9PL, UK.
L ChristieWolfson Molecular Imaging Centre, University of Manchester, Manchester, M20 3LJ, UK.
C B LawrenceDivision of Neuroscience and Experimental Psychology, Faculty of Biology, Medicine and Health, School of Biological Sciences, University of Manchester, Manchester, M13 9PL, UK.
K HerholzDivision of Neuroscience and Experimental Psychology, Faculty of Biology, Medicine and Health, School of Biological Sciences, University of Manchester, Manchester, M13 9PL, UK.
C A ParkerGlaxoSmithKline, Gunnels Wood Road, Stevenage, SG1 2NY, UK.
R HinzWolfson Molecular Imaging Centre, University of Manchester, Manchester, M20 3LJ, UK.
H BoutinDivision of Neuroscience and Experimental Psychology, Faculty of Biology, Medicine and Health, School of Biological Sciences, University of Manchester, Manchester, M13 9PL, UK. herve.boutin@manchester.ac.uk.ORCID http://orcid.org/0000-0002-0029-5246
Manchester Academic Health Science Centre · GBUniversity of Manchester · GBGlaxoSmithKline (United Kingdom) · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long-term memory requires stable protein synthesis and is altered in Alzheimer's disease (AD). This study aimed to implement a method to measure the cerebral protein synthesis rate (PSR) with [

Indexed as

Alzheimer DiseaseAnimalsAnisomycinCross-Sectional StudiesDisease Models, AnimalLeucineLongitudinal StudiesPositron-Emission TomographyRatsRats, Inbred F344Rats, WistarAnisomycinLeucine[11C]LeucineAlzheimer’s DiseaseAmino Acid PETProtein Synthesis rateTgF344-AD Rats

Identifiers

PMID36538180
PMCPMC10172255
OpenAlexW4312019895

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.