Trial reportLasers in medical science2022
Evaluation of the effects of photobiomodulation with different laser application doses on injection pain in children: a randomized clinical trial.
Trial report in Lasers in medical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- The role of photobiomodulation in minimizing pain during dental injections in adults and children: a systematic review and meta-analysis.Lasers in medical science · 2025Pooled it
- The prophylactic effect of photobiomodulation therapy on pain perception due to infiltration injection: a randomized clinical trial.Clinical oral investigations · 2024Trial
- Effect of photobiomodulation on pain perception during local anesthesia in children: a systematic review and meta-analysis.Journal of dental anesthesia and pain medicine · 2026Review
- Effect of photo-bio-modulation on pain perception with inferior alveolar nerve block among children: A split mouth study.Bioinformation · 2025Article
- The efficacy of photobiomodulation on dental injection pain: a systematic review of randomized clinical trials.Journal of dental anesthesia and pain medicine · 2024Review
- Effect of Photobiomodulation Therapy With an 810-nm Diode Laser on Pain Perception Associated With Dental Injections in Children: A Double-Blind Randomized Controlled Clinical Trial.Journal of lasers in medical sciences · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The utilization of photobiomodulation (PBM) to decrease the experience of pain during the application of local anesthesia (LA) has been reported in a limited number of studies with children. However, currently, there is no complete consensus regarding its efficacy and application doses. The objective of the clinical trial was to assess the effects of PBM with three different laser application doses (with different power values) plus 10% lidocaine topical anesthetic and to compare them with placebo + 10% lidocaine topical anesthetic on LA injection pain in children. A prospective, parallel-arm, randomized, triple-blind clinical trial was conducted with 160 children aged 6 to 12 years (79 girls and 81 boys; 80 maxillary and 80 mandibular primary first molars). The children were divided into 4 groups with an equal number of subjects in each group. Before topical anesthetic usage, a laser with a power of 0.3 W, 0.4 W, and 0.5 W was applied in Groups 1, 2, and 3, respectively (a diode laser: 940 nm; continuous mode; 20 s for each group). The energy density was calculated as 69 J/cm
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.