Evidence map›Paper›PMID 36538100›Full record

ArticleInsights into imaging2022

Radiomics assessment of carotid intraplaque hemorrhage: detecting the vulnerable patients.

Shuai Zhang, Lin Gao, Bing Kang, Xinxin Yu, Ran Zhang, Ximing Wang

Open access · goldAbstract read
In one paragraph

Article in Insights into imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
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  11. Quality assessment of radiomics models in carotid plaque: a systematic review.Quantitative imaging in medicine and surgery · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Shuai ZhangThe School of Medicine, Shandong First Medical University, No. 6699, Qingdao Road, Huaiyin District, Jinan, China.
Lin GaoThe School of Medicine, Shandong First Medical University, No. 6699, Qingdao Road, Huaiyin District, Jinan, China.
Bing KangDepartment of Radiology, Shandong Provincial Hospital Affliated to Shandong First Medical University, No. 324 Jingwu Road, Jinan, 250021, China.
Xinxin YuDepartment of Radiology, Shandong Provincial Hospital Affliated to Shandong First Medical University, No. 324 Jingwu Road, Jinan, 250021, China.
Ran ZhangHuiying Medical Technology Co. Ltd., 66 Xixiaokou Road, Haidian District, Beijing, China.
Ximing WangDepartment of Radiology, Shandong Provincial Hospital Affliated to Shandong First Medical University, No. 324 Jingwu Road, Jinan, 250021, China. wangximing369@yeah.net.ORCID http://orcid.org/0000-0001-5136-8057
Shandong Provincial Hospital · CNShandong First Medical University · CN

Funding

Academic promotion programme of Shandong First Medical University 2019QL023National Natural Science Foundation of China 81571672National Natural Science Foundation of China 8187354
6 · The paper itself

Abstract

backgroundIntraplaque hemorrhage (IPH), one of the key features of vulnerable plaques, has been shown to be associated with increased risk of stroke. The aim is to develop and validate a CT-based radiomics nomogram incorporating clinical factors and radiomics signature for the detection of IPH in carotid arteries.

methodsThis retrospective study analyzed the patients with carotid plaques on CTA from January 2013 to January 2021 at two different institutions. Radiomics features were extracted from CTA images. Demographics and CT characteristics were evaluated to build a clinical factor model. A radiomics signature was constructed by the least absolute shrinkage and selection operator method. A radiomics nomogram combining the radiomics signature and independent clinical factors was constructed. The area under curves of three models were calculated by receiver operating characteristic analysis.

resultsA total of 46 patients (mean age, 60.7 years ± 10.4 [standard deviation]; 36 men) with 106 carotid plaques were in the training set, and 18 patients (mean age, 61.4 years ± 10.1; 13 men) with 38 carotid plaques were in the external test sets. Stenosis was the independent clinical factor. Eight features were used to build the radiomics signature. The area under the curve (AUC) of the radiomics nomogram was significantly higher than that of the clinical factor model in both the training (p = 0.032) and external test (p = 0.039) sets.

conclusionsA CT-based radiomics nomogram showed satisfactory performance in distinguishing carotid plaques with and without intraplaque hemorrhage.

Indexed as

AtherosclerosisCarotid arteryComputed tomographyIntraplaque hemorrhageRadiomics

Identifiers

PMID36538100
PMCPMC9768061
OpenAlexW4312114848

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.