Evidence map›Paper›PMID 36537896›Full record

ReviewRadiology2023

Yiu Ming Khor, Sarah A M Cuddy, Vasvi Singh, Rodney H Falk, Marcelo F Di Carli, Sharmila Dorbala

Open access · greenAbstract readReview
In one paragraph

Review in Radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Yiu Ming KhorFrom the Department of Nuclear Medicine and Molecular Imaging, Singapore General Hospital, Singapore (Y.M.K.); Division of Nuclear Medicine and Molecular Imaging, Department of Radiology (Y.M.K., V.S., M.F.D.C., S.D.), Cardiac Amyloidosis Program, Division of Cardiology, Department of Medicine (S.A.M.C., R.H.F., S.D.), and CV Imaging Program, Cardiovascular Division and Department of Radiology (S.A.M.C., V.S., M.F.D.C., S.D.), Brigham and Women's Hospital and Harvard Medical School, 70 Francis St, Boston, MA 02115; and Midwest Heart and Vascular Specialists, HCA Midwest Health, Kansas City, Mo (V.S.).ORCID 0000-0002-4307-1349
Sarah A M CuddyFrom the Department of Nuclear Medicine and Molecular Imaging, Singapore General Hospital, Singapore (Y.M.K.); Division of Nuclear Medicine and Molecular Imaging, Department of Radiology (Y.M.K., V.S., M.F.D.C., S.D.), Cardiac Amyloidosis Program, Division of Cardiology, Department of Medicine (S.A.M.C., R.H.F., S.D.), and CV Imaging Program, Cardiovascular Division and Department of Radiology (S.A.M.C., V.S., M.F.D.C., S.D.), Brigham and Women's Hospital and Harvard Medical School, 70 Francis St, Boston, MA 02115; and Midwest Heart and Vascular Specialists, HCA Midwest Health, Kansas City, Mo (V.S.).ORCID 0000-0002-2124-2151
Vasvi SinghFrom the Department of Nuclear Medicine and Molecular Imaging, Singapore General Hospital, Singapore (Y.M.K.); Division of Nuclear Medicine and Molecular Imaging, Department of Radiology (Y.M.K., V.S., M.F.D.C., S.D.), Cardiac Amyloidosis Program, Division of Cardiology, Department of Medicine (S.A.M.C., R.H.F., S.D.), and CV Imaging Program, Cardiovascular Division and Department of Radiology (S.A.M.C., V.S., M.F.D.C., S.D.), Brigham and Women's Hospital and Harvard Medical School, 70 Francis St, Boston, MA 02115; and Midwest Heart and Vascular Specialists, HCA Midwest Health, Kansas City, Mo (V.S.).
Rodney H FalkFrom the Department of Nuclear Medicine and Molecular Imaging, Singapore General Hospital, Singapore (Y.M.K.); Division of Nuclear Medicine and Molecular Imaging, Department of Radiology (Y.M.K., V.S., M.F.D.C., S.D.), Cardiac Amyloidosis Program, Division of Cardiology, Department of Medicine (S.A.M.C., R.H.F., S.D.), and CV Imaging Program, Cardiovascular Division and Department of Radiology (S.A.M.C., V.S., M.F.D.C., S.D.), Brigham and Women's Hospital and Harvard Medical School, 70 Francis St, Boston, MA 02115; and Midwest Heart and Vascular Specialists, HCA Midwest Health, Kansas City, Mo (V.S.).
Marcelo F Di CarliFrom the Department of Nuclear Medicine and Molecular Imaging, Singapore General Hospital, Singapore (Y.M.K.); Division of Nuclear Medicine and Molecular Imaging, Department of Radiology (Y.M.K., V.S., M.F.D.C., S.D.), Cardiac Amyloidosis Program, Division of Cardiology, Department of Medicine (S.A.M.C., R.H.F., S.D.), and CV Imaging Program, Cardiovascular Division and Department of Radiology (S.A.M.C., V.S., M.F.D.C., S.D.), Brigham and Women's Hospital and Harvard Medical School, 70 Francis St, Boston, MA 02115; and Midwest Heart and Vascular Specialists, HCA Midwest Health, Kansas City, Mo (V.S.).ORCID 0000-0003-3119-025X
Sharmila DorbalaFrom the Department of Nuclear Medicine and Molecular Imaging, Singapore General Hospital, Singapore (Y.M.K.); Division of Nuclear Medicine and Molecular Imaging, Department of Radiology (Y.M.K., V.S., M.F.D.C., S.D.), Cardiac Amyloidosis Program, Division of Cardiology, Department of Medicine (S.A.M.C., R.H.F., S.D.), and CV Imaging Program, Cardiovascular Division and Department of Radiology (S.A.M.C., V.S., M.F.D.C., S.D.), Brigham and Women's Hospital and Harvard Medical School, 70 Francis St, Boston, MA 02115; and Midwest Heart and Vascular Specialists, HCA Midwest Health, Kansas City, Mo (V.S.).ORCID 0000-0003-1462-1185
Brigham and Women's Hospital · US

Funding

Early Detection of Transthyretin Cardiac Amyloidosis: Defining a Novel Target for HFpEF Treatment and Prevention in Late LifeR01HL150342 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI DORBALA, SHARMILA, SHAH, AMIL M · 2020 to 2023
$4.1M
Molecular Imaging of Primary Amyloid CardiomyopathyR01HL130563 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI DORBALA, SHARMILA, FALK, RODNEY H · 2016 to 2019
$3.3M
Mentoring Patient Oriented Research in Innovative Imaging and High-dimensional Data Approaches to Improve Outcomes in Cardiac AmyloidosisK24HL157648 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI DORBALA, SHARMILA · 2021 to 2025
$612k
NHLBI NIH HHS K24 HL157648NHLBI NIH HHS R01 HL130563NHLBI NIH HHS R01 HL150342
6 · The paper itself

Abstract

Transthyretin cardiac amyloidosis (ATTR-CA) is an overlooked cause of heart failure, with substantial morbidity and mortality. The emergence of several novel therapies has fueled the interest in early and accurate diagnosis of ATTR-CA so that potentially life-saving pharmacologic therapy can be administered in a timely manner. The most promising imaging modality and biomarker is SPECT imaging with technetium 99m (

Indexed as

Amyloid Neuropathies, FamilialAmyloidosisCardiomyopathiesDiphosphatesDiphosphonatesHeartHumansPrealbuminRadionuclide ImagingRadiopharmaceuticalsDiphosphatesDiphosphonatesdiphosphoric acidhydroxymethanediphosphonic acidPrealbuminRadiopharmaceuticals

Identifiers

PMID36537896
PMCPMC9885342
OpenAlexW4311993840

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.