Evidence map›Paper›PMID 36537825›Full record

ArticleMicrobiology spectrum2023

Molecular Basis of the Toxigenic Vibrio cholerae O1 Serotype Switch from Ogawa to Inaba in Haiti.

Taylor K Paisie, Melanie N Cash, Massimiliano S Tagliamonte, Afsar Ali, J Glenn Morris, Marco Salemi, Carla Mavian

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
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  5. bioRxiv : the preprint server for biology · 2025
    Article
  6. Article
  7. Article
  8. Allelic variations and gene cluster modularity act as nonlinear bottlenecks for cholera emergence.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Taylor K PaisieDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, Florida, USA.
Melanie N CashDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, Florida, USA.
Massimiliano S TagliamonteDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, Florida, USA.ORCID 0000-0003-2699-7331
Afsar AliEmerging Pathogens Institute, University of Florida, Gainesville, Florida, USA.
J Glenn MorrisEmerging Pathogens Institute, University of Florida, Gainesville, Florida, USA.ORCID 0000-0001-9347-1984
Marco SalemiDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, Florida, USA.ORCID 0000-0003-0136-2102
Carla MavianDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, Florida, USA.ORCID 0000-0003-3819-5520
University of Florida · US

Funding

Recurrence of Cholera in Haiti: Exploration of Contributing Factors and Intervention StrategiesR01AI126357 · NIAID · UNIVERSITY OF FLORIDA · PI John Glenn Morris · 2016 to 2026
$7.3M
Cholera persistence, transmission, and clinical illness in HaitiR01AI128750 · NIAID · UNIVERSITY OF FLORIDA · PI MORRIS, JOHN GLENN · 2017 to 2021
$3.6M
Cholera Transmission in Gressier Region, HaitiR01AI097405 · NIAID · UNIVERSITY OF FLORIDA · PI MORRIS, JOHN GLENN · 2012 to 2015
$2.7M
NIAID NIH HHS R01 AI097405NIAID NIH HHS R01 AI126357NIAID NIH HHS R01 AI128750
6 · The paper itself

Abstract

Toxigenic Vibrio cholerae O1 serotype Ogawa was introduced involuntarily into Haiti in October 2010, and virtually all of the clinical strains isolated during the first 5 years of the epidemic were Ogawa. Inaba strains were identified intermittently prior to 2015, with diverse mutations resulting in a common phenotype. In 2015, the percentage of clinical infections due to the Inaba serotype began to rapidly increase, with Inaba supplanting Ogawa as the dominant serotype during the subsequent 4 years. We investigated the molecular basis of the serotype switch and confirmed that all Inaba strains had the same level of mRNA expression of the

Indexed as

CholeraVibrio cholerae O1HaitiHumansSerogroupSerotypingcholeraevolutionInabaOgawaphylodynamicsserotype switch

Identifiers

PMID36537825
PMCPMC9927444
OpenAlexW4312018327

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.