Evidence map›Paper›PMID 36537806›Full record

ArticleMicrobiology spectrum2023

Antimicrobial Activity of Tannic Acid

Weigang Wang, Jing Cao, Jing Yang, Xiaoran Niu, Xiaoxuan Liu, Yu Zhai, Cuixin Qiang, Yanan Niu, Zhirong Li, Ning Dong and 6 more

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Biological Mechanisms of Polyphenols againstInfectious disorders drug targets · 2025
    Pooled it
  2. Virulence · 2026
    Article
  3. Tannic acid as a multi-target regulator of intestinal barrier function in livestock.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Weigang Wang *The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.ORCID 0000-0001-6529-1054
Jing Cao *The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Jing Yang *The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Xiaoran NiuThe Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Xiaoxuan LiuThe Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Yu ZhaiThe Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Cuixin QiangThe Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Yanan NiuThe Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Zhirong LiThe Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Ning DongThe Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Baojiang WenThe Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Zirou OuyangThe Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Yulian ZhangThe Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Jiayiren LiThe Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Min ZhaoThe Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Jianhong ZhaoThe Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.ORCID 0000-0002-7368-7961
Hebei Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clostridioides difficile infection (CDI), recurrently reported as an urgent threat owing to its increased prevalence and mortality, has attracted significant attention. As the use of antibiotics to treat CDI has many limitations, such as high recurrence rate, the need to actively seek and develop other drugs that can effectively treat CDI with fewer side effects has become a key issue in CDI prevention and treatment. This study aimed to evaluate the inhibitory effect of Galla chinensis (GC) and its main component, tannic acid (TA), against C. difficile

Indexed as

Clostridioides difficileClostridium InfectionsTanninsAnimalsAnti-Bacterial AgentsClostridioidesDiarrheaDrugs, Chinese HerbalMicePolyphenolsAnti-Bacterial AgentsDrugs, Chinese HerbalGalla chinensisPolyphenolstannic acidTanninsantibioticsClostridioides difficilemicrobiotamouse modelsporetannic acidtoxin

Identifiers

PMID36537806
PMCPMC9927261
OpenAlexW4312019219

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.