Evidence map›Paper›PMID 36537790›Full record

ArticleInfection and immunity2023

The Two-Component System YesMN Promotes Pneumococcal Host-to-Host Transmission and Regulates Genes Involved in Zinc Homeostasis.

M Ammar Zafar, Alicia Costa-Terryl, Taylor M Young

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Influenza A Virus Coinfection AltersbioRxiv : the preprint server for biology · 2026
    Article
  3. Mechanisms of bacterial host-to-host transmission.Microbiology and molecular biology reviews : MMBR · 2025
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

M Ammar ZafarDepartment of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.ORCID 0000-0002-3737-0422
Alicia Costa-TerrylDepartment of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Taylor M YoungDepartment of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Wake Forest University · US

Funding

Tumor Tissue CoreP30CA012197 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Ruben A. Mesa · 1985 to 2026
$55.4M
TRAINING PROGRAM IN IMMUNOLOGY AND PATHOGENESIST32AI007401 · NIAID · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Martha Ann Alexander-Miller · 1991 to 2026
$4.4M
Determining the mechanisms by which YesMN drives pneumococcal host-to-host transmissionR21AI154047 · NIAID · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ZAFAR, MUHAMMAD AMMAR · 2020 to 2021
$426k
NCI NIH HHS P30 CA012197NIAID NIH HHS R21 AI154047NIAID NIH HHS T32 AI007401
6 · The paper itself

Abstract

The ability to sense and respond rapidly to the dynamic environment of the upper respiratory tract (URT) makes Streptococcus pneumoniae (

Indexed as

Pneumococcal InfectionsStreptococcus pneumoniaeHomeostasisHumansNosePolysaccharidesPolysaccharidesanimal modelscoinfectioninfluenzaStreptococcus pneumoniaetransmissiontwo-component regulatory systems

Identifiers

PMID36537790
PMCPMC9872629
OpenAlexW4312018770

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.