Evidence map›Paper›PMID 36537525›Full record

ArticlePediatric diabetes2022

ISPAD Clinical Practice Consensus Guidelines 2022: Management of cystic fibrosis-related diabetes in children and adolescents.

Katie Larson Ode, Manfred Ballman, Alberto Battezzati, Amanda Brennan, Christine L Chan, Shihab Hameed, Heba M Ismail, Andrea Kelly, Antoinette M Moran, Remi Rabasa-Lhoret and 2 more

Registry-linked trialAbstract read
In one paragraph

Article in Pediatric diabetes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07688070 (The Effect of Verapamil on Beta Cell Function in Adolescents and Adults With Cystic Fibrosis-related Dysglycemia), which is not on this map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07688070 phase2not yet recruitingnot on this mapstarted 2026, after this paper: background citation

The Effect of Verapamil on Beta Cell Function in Adolescents and Adults With Cystic Fibrosis-related Dysglycemia

TypeinterventionalSponsorRhode Island HospitalRan2026 to 2028Enrolled30ConditionsCystic Fibrosis Related Diabetes, Cystic Fibrosis (CF), Abnormal Glucose ToleranceArmsVerapamil Hydrochloride
3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Trial
  2. Exogenous insulin does not reduce protein catabolism in pre-diabetic cystic fibrosis patients: A randomized clinical trial.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2025
    Trial
  3. Trial
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. The endocrine complications of cystic fibrosis.Nature reviews. Endocrinology · 2026
    Review
  10. Review
  11. Approach to the Patient With Pancreatogenic Diabetes.The Journal of clinical endocrinology and metabolism · 2026
    Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Katie Larson OdeUniversity of Iowa Stead Family Children's Hospital, University of Iowa, Iowa City, Iowa, USA.
Manfred BallmanUniversity Medicine Rostock, Rostock, Mecklenburg-Vorpommern, Germany.
Alberto BattezzatiInternational Center for the Assessment of Nutritional Status, DeFENS, University of Milan, Milan, Italy.
Amanda BrennanManchester Adult Cystic Fibrosis Centre, Manchester University NHS Foundation Trust, Manchester, UK.
Christine L ChanUniversity of Colorado Anschutz Medical Campus, Children's Hospital Colorado, Aurora, Colorado, USA.
Shihab HameedSydney Children's Hospital, Randwick and Royal North Shore Hospital, St. Leonards, New South Wales, Australia.
Heba M IsmailDepartment of Pediatrics, Pediatric Endocrinology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Andrea KellyDepartment of Pediatrics, The University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Antoinette M MoranDepartment of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.
Remi Rabasa-LhoretDivision of Experiemental Medicine, Montreal Clinical Research institute, Montreal, Canada.
Nichole A SaxbyWomen's and Children's Services, Royal Hobart Hospital, Hobart, Tasmania, Australia.
Maria E CraigThe Children's Hospital at Westmead, University of Sydney, Sydney, New South Wales, Australia.

Funding

Translation CoreP30DK097512 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI Carmella Evans-Molina · 2015 to 2026
$17.4M
Evaluation of the entero-insular (incretin) axis in cystic fibrosis-competitive renewal.R01DK097830 · NIDDK · CHILDREN'S HOSP OF PHILADELPHIA · PI KELLY, ANDREA BRIDGET, RICKELS, MICHAEL R · 2012 to 2024
$5.7M
NIDDK NIH HHS P30 DK097512NIDDK NIH HHS R01 DK097830
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cystic FibrosisDiabetes MellitusAdolescentChildConsensusCystic Fibrosis Transmembrane Conductance RegulatorHumansCystic Fibrosis Transmembrane Conductance RegulatoradolescentsCFTR modulatorchildrencystic fibrosis related diabetesHEMT therapy

Identifiers

PMID36537525
PMCPMC10108242

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.