Evidence map›Paper›PMID 36537400›Full record

ArticleIndian journal of pharmacology

Assessment of prescribing pattern of drugs and completeness of prescriptions as per the World Health Organization prescribing indicators in various Indian tertiary care centers: A multicentric study by Rational Use of Medicines Centers-Indian Council of Medical Research network under National Virtual Centre Clinical Pharmacology activity.

R Joshi, B Medhi, A Prakash, S Chandy, J Ranjalkar, H R Bright, J Basker, L Govindraj, P K Chugh, C D Tripathi and 43 more

Abstract readMulticenter Study
In one paragraph

Article in Indian journal of pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Observational
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Profile of Drug Utilization in Patients with Rare Diseases in Tuscany, Italy: A Population-Based Study.International journal of environmental research and public health · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

53 authors.

R JoshiDepartment of Pharmacology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
B MedhiDepartment of Pharmacology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
A PrakashDepartment of Pharmacology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
S ChandyDepartment of Pharmacology and Clinical Pharmacology, Christian Medical College, Vellore, Tamil Nadu, India.
J RanjalkarDepartment of Pharmacology and Clinical Pharmacology, Christian Medical College, Vellore, Tamil Nadu, India.
H R BrightDepartment of Pharmacology and Clinical Pharmacology, Christian Medical College, Vellore, Tamil Nadu, India.
J BaskerDepartment of Pharmacology and Clinical Pharmacology, Christian Medical College, Vellore, Tamil Nadu, India.
L GovindrajDepartment of Pharmacology and Clinical Pharmacology, Christian Medical College, Vellore, Tamil Nadu, India.
P K ChughVardhman Mahavir Medical College, New Delhi, India.
C D TripathiVardhman Mahavir Medical College, New Delhi, India.
D K BadyalDepartment of Pharmacology, Christian Medical College, Ludhiana, Punjab, India.
S BalakrishnanDepartment of Pharmacology, All India Institute of Medical Sciences, Bhopal, India.
R JhajDepartment of Pharmacology, All India Institute of Medical Sciences, Bhopal, India.
A K ShuklaDepartment of Pharmacology, All India Institute of Medical Sciences, Bhopal, India.
S AtalDepartment of Pharmacology, All India Institute of Medical Sciences, Bhopal, India.
A NajmiDepartment of Pharmacology, All India Institute of Medical Sciences, Bhopal, India.
A BanerjeeDepartment of Pharmacology, All India Institute of Medical Sciences, Bhopal, India.
S KamatDepartment of Pharmacology and Therapeutics, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India.
R K TripathiDepartment of Pharmacology and Therapeutics, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India.
Y C ShettyDepartment of Pharmacology and Therapeutics, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India.
U ParmarDepartment of Pharmacology and Therapeutics, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India.
N RegeDepartment of Pharmacology and Therapeutics, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India.
H DikshitDepartment of Pharmacology, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India.
H MishraDepartment of Pharmacology, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India.
S S RoyDepartment of Pharmacology, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India.
S ChatterjeeDepartment of Pharmacology, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India.
A HazraDepartment of Pharmacology, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India.
M BhattacharyaDepartment of Pharmacology, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India.
D DasDepartment of Pharmacology, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India.
N TrivediDepartment of Pharmacology, Government Medical College, Baroda, Gujarat, India.
P ShahDepartment of Pharmacology, Government Medical College, Baroda, Gujarat, India.
J ChauhanDepartment of Pharmacology, Government Medical College, Baroda, Gujarat, India.
C DesaiDepartment of Pharmacology, B.J. Medical College, Ahmedabad, Gujarat, India.
A M GandhiDepartment of Pharmacology, B.J. Medical College, Ahmedabad, Gujarat, India.
P P PatelDepartment of Pharmacology, B.J. Medical College, Ahmedabad, Gujarat, India.
S ShahDepartment of Pharmacology, B.J. Medical College, Ahmedabad, Gujarat, India.
S ShethDepartment of Pharmacology, B.J. Medical College, Ahmedabad, Gujarat, India.
R RaveendranDepartment of Pharmacology, Jawaharlal Institute of Post Medical Education and Research, Puducherry, India.
J MathaiyanDepartment of Pharmacology, Jawaharlal Institute of Post Medical Education and Research, Puducherry, India.
S ManikandanDepartment of Pharmacology, Jawaharlal Institute of Post Medical Education and Research, Puducherry, India.
G JeevithaDepartment of Pharmacology, Jawaharlal Institute of Post Medical Education and Research, Puducherry, India.
P GuptaDepartment of Pharmacology, All India Institute of Medical Sciences, New Delhi, India.
S C SarangiDepartment of Pharmacology, All India Institute of Medical Sciences, New Delhi, India.
H N YadavDepartment of Pharmacology, All India Institute of Medical Sciences, New Delhi, India.
S SinghDepartment of Pharmacology, All India Institute of Medical Sciences, New Delhi, India.
S KaushalDepartment of Pharmacology, Dayanand Medical college and Hospital, Ludhiana, Punjab, India.
S AroraDepartment of Pharmacology, Dayanand Medical college and Hospital, Ludhiana, Punjab, India.
K GuptaDepartment of Pharmacology, Dayanand Medical college and Hospital, Ludhiana, Punjab, India.
S JainDepartment of Pharmacology, Dayanand Medical college and Hospital, Ludhiana, Punjab, India.
J J CherianIndian Council of Medical Research, New Delhi, India.
N S ChatterjeeIndian Council of Medical Research, New Delhi, India.
R KaulIndian Council of Medical Research, New Delhi, India.
N A KshirsagarIndian Council of Medical Research, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe rational use of medicines as per the World Health Organization (WHO) should be practiced globally. However, data regarding the completeness of the prescriptions and their rational use is lacking from developing countries like India. Thus, the aim of this study was to assess the prescribing patterns of drugs and completeness of prescriptions as per WHO core drug use and complementary indicators to provide real-life examples for the Indian Council of Medical Research (ICMR) online prescribing skill course for medical graduates.

methodsPrescriptions of the patients, fulfilling inclusion criteria, attending Outpatient Departments of various specialties of tertiary care hospitals, were collected by thirteen ICMR Rational use of medicines centers located in tertiary care hospitals, throughout India. Prescriptions were evaluated for rational use of medicines according to the WHO guidelines and for appropriateness as per standard treatment guidelines using a common protocol approved by local Ethics committees.

resultsAmong 4838 prescriptions, an average of about three drugs (3.34) was prescribed to the patients per prescription. Polypharmacy was noted in 83.05% of prescriptions. Generic drugs were prescribed in 47.58% of the prescriptions. Further, antimicrobials were prescribed in 17.63% of the prescriptions and only 4.98% of prescriptions were with injectables. During the prescription evaluation, 38.65% of the prescriptions were incomplete due to multiple omissions such as dose, duration, and formulation.

conclusionMost of the parameters in the present study were out of the range of WHO-recommended prescribing indicators. Therefore, effective intervention program, like training, for the promotion of rational drug use practice was recommended to improve the prescribing pattern of drugs and the quality of prescriptions all over the country.

Indexed as

Biomedical ResearchPharmacology, ClinicalDrug PrescriptionsHumansPractice Patterns, Physicians'Tertiary Health CareWorld Health OrganizationAppropriatenessfixed-dose combinationnational list of essential medicinesprescription auditrational use of drugs

Identifiers

PMID36537400
PMCPMC9846909

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