ArticleInternational journal of ophthalmology2022
Clinical feature and predictive factor analysis for spontaneous regression of retinopathy of prematurity in a Chinese population.
Article in International journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 3 citations in OpenAlex.
- Analysis of influencing factors for progression from type 2 to type 1 in retinopathy of prematurity.Frontiers in pediatrics · 2026Article
- The association between red blood cell transfusion timing and the development of retinopathy of prematurity: Application of the two-phase theory.Acta ophthalmologica · 2025Article
- Nomogram to predict severe retinopathy of prematurity in Southeast China.International journal of ophthalmology · 2024Article
- Neonatal retinal hemorrhage and retinopathy of prematurity: a critical review of current practices and future directions.Therapeutic advances in ophthalmologyReview
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo investigate the ratio of spontaneous regression of retinopathy of prematurity (ROP) and to explore the possible relevant predictive factors.
methodsA retrospective review of 405 infants who were diagnosed with ROP and mother during pregnancy were collected. Stage, zone, and duration of ROP were recorded. Statistical analysis was performed on 51 possible predictive factors.
resultsTotally 356 infants showed spontaneous regression. The incidence was 100%, 95.3%, and 22.7% in stage 1, 2, and 3, respectively. The 13.4% of the ROP with plus disease eventually resolved spontaneously. All affected eyes of aggressive posterior retinopathy of prematurity (AP-ROP) failed to spontaneously regress. The mean duration of ROP was 7.2wk in patients with spontaneous resolution of ROP. Days of mechanical ventilation (OR=0.981, 95%CI, 0.965-0.997,
conclusionMost mild ROP can spontaneously resolve. Active treatment is still recommended for stage 3 ROP, zone I ROP, AP-ROP, and ROP with plus disease. Prolonged mechanical ventilation and concurrent retinal hemorrhage reduce the likelihood of spontaneous ROP resolution. The pattern of delivery and the mother's anemia during pregnancy can also affect the prognosis of ROP.
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