ArticleClinical epidemiology2022
The Global Burden of Appendicitis in 204 Countries and Territories from 1990 to 2019.
Article in Clinical epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Evidence map of appendicitis - a living systematic review with meta-analyses.Langenbeck's archives of surgery · 2026Pooled it
- Role of intraoperative antibiotics wound irrigation in reducing surgical site infection following open appendectomy: a randomized controlled trial.BMC surgery · 2025Trial
- Epidemiology of appendicitis in Ecuador, 2004-2024: a national time-series analysis of incidence, trends, geographic variation, and case-fatality rates.Lancet regional health. Americas · 2026Article
- Non-operative management of acute appendicitis is not readily generalisable to Honduras: a viewpoint from a low-resource setting.Journal of global health · 2026Article
- Laparoscopic appendectomy for complicated appendicitis with periappendiceal abscess versus without abscess in children: a prospective cohort study.Surgical endoscopy · 2026Review
- Appendicitis burden in Africa, 2010-2023: temporal trends, pandemic-era deviations, and projections to 2030.Tropical medicine and health · 2026Article
- Subhepatic appendicitis mimicking biliary disease: diagnostic pitfalls and laparoscopic management.Journal of surgical case reports · 2026Article
- A Hybrid Model with Quantum Feature Map Based on CNN and Vision Transformer for Clinical Support in Diagnosis of Acute Appendicitis.Biomedicines · 2026Article
- Global, Regional, and National Burden of Acute Abdominal Conditions in Females-Appendicitis, Ectopic Pregnancy, Paralytic Ileus and Intestinal Obstruction, and Urolithiasis, 1990-2021: A Systematic Analysis for the Global Burden of Disease Study 2021 with ARIMA Projections to 2030.International journal of women's health · 2026Article
- Development and validation of a diagnostic nomogram based on peripheral blood composite inflammatory markers for complicated acute appendicitis: a retrospective study.Frontiers in surgery · 2026Article
- Glucose-to-albumin ratio and mortality in ICU patients with acute pancreatitis.Open medicine (Warsaw, Poland) · 2026Article
- Drivers of No-Show for Ambulatory Appendectomy at Kyabirwa Surgical Center, Jinja City, Uganda.Cureus · 2025Article
- Article
- Reduced recurrence rate with a targeted approach in uncomplicated appendicitis treated with endoscopic directWorld journal of gastroenterology · 2025Article
- Appendicitis.Nature reviews. Disease primers · 2025Review
- Application value of abdominal ultrasonography in the diagnosis of pediatric patients aged 3-12 years with acute appendicitis.World journal of gastrointestinal surgery · 2025Article
- Observational
- The occurrence of appendicitis varies according to latitudes and seasons: A French national retrospective study.Environmental epidemiology (Philadelphia, Pa.) · 2025Article
- PACU discharge: equally safe and more cost-effective than floor admission for uncomplicated laparoscopic appendectomy.Perioperative medicine (London, England) · 2025Article
- Appendicitis burden, trends, and inequalities in Europe, 1990-2019: a population-based study.Gastroenterology report · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Appendicitis is a common surgical emergency. This study aimed to estimate the worldwide burden and trends of appendicitis from 1990 to 2019. Methods: Data on appendicitis were derived from the Global Burden of Disease 2019. Incidence and disability-adjusted life-years (DALYs) data were analyzed at global, regional, and national levels and stratified by sex, age, and socio-demographic index. The estimated annual percentage change and relative change were used to assess changing trends. Pearson's correlation test was used to assess the correlation between different measures. Results: Global incidence grew by 63.55% between 1990 and 2019, age-standardized incidence rate climbed by an estimated percentage change of 0.58 per year, whereas the number of DALY declined by 31.93% during the same period, with an estimated annual percentage change of -2.77. In 2019, the areas of Andean Latin America and the Caribbean had the highest age-standardized rates of incidence and DALYs. While South Asia saw the largest increase in age-standardized incidence rates, Andean Latin America saw the biggest decline in age-standardized rates of incidence and DALYs. At the national level, Bangladesh, Bhutan, and Peru were the top three countries in terms of age-standardized incidence rates in 2019, and Honduras, Haiti, and the Central African Republic held the highest age-standardized DALY rates. Ethiopia experienced the most age-standardized incidence rate increase, and Peru saw the largest decline in age-standardized rate of incidence and DALYs. Significant negative correlations between age-standardized DALY rates and socio-demographic index, between estimated annual percentage change and age-standardized incidence rates, were observed at the national level. Conclusion: Appendicitis remains a major global health concern. Although the trends in DALYs decreased, the burden of incidence increased from 1990 to 2019. Policymakers should create health policies adapted to local conditions to manage the burden of appendicitis globally.
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