Evidence map›Paper›PMID 36536872›Full record

ArticleVaccine: X2023

COVID-19 vaccination and the skin to deltoid MUSCLE distance in adults with diabetes.

Marjan Doppen, Ali Mirjalili, Matire Harwood, Allie Eathorne, Irene Braithwaite, Jonathan Bong, Louis Kirton, Ruth Semprini, Mark Weatherall, Alex Semprini and 6 more

Open access · goldAbstract read
In one paragraph

Article in Vaccine: X, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

Marjan DoppenMedical Research Institute of New Zealand, Medical Research Institute of New Zealand, Private Bag 7902, Wellington 6242, New Zealand.
Ali MirjaliliUniversity of Auckland, Building 409, 24 Symonds Street, City Campus, Auckland, New Zealand.
Matire HarwoodMedical Research Institute of New Zealand, Medical Research Institute of New Zealand, Private Bag 7902, Wellington 6242, New Zealand.
Allie EathorneMedical Research Institute of New Zealand, Medical Research Institute of New Zealand, Private Bag 7902, Wellington 6242, New Zealand.
Irene BraithwaiteMedical Research Institute of New Zealand, Medical Research Institute of New Zealand, Private Bag 7902, Wellington 6242, New Zealand.
Jonathan BongCapital and Coast District Health Board, 69 Riddiford Street, Newtown, Wellington 6021, New Zealand.
Louis KirtonMedical Research Institute of New Zealand, Medical Research Institute of New Zealand, Private Bag 7902, Wellington 6242, New Zealand.
Ruth SempriniMedical Research Institute of New Zealand, Medical Research Institute of New Zealand, Private Bag 7902, Wellington 6242, New Zealand.
Mark WeatherallUniversity of Otago Wellington, 23A Mein Street, Newtown, Wellington 6242, New Zealand.
Alex SempriniMedical Research Institute of New Zealand, Medical Research Institute of New Zealand, Private Bag 7902, Wellington 6242, New Zealand.
Ciléin KearnsMedical Research Institute of New Zealand, Medical Research Institute of New Zealand, Private Bag 7902, Wellington 6242, New Zealand.
Melissa BlackMedical Research Institute of New Zealand, Medical Research Institute of New Zealand, Private Bag 7902, Wellington 6242, New Zealand.
Stacey KungMedical Research Institute of New Zealand, Medical Research Institute of New Zealand, Private Bag 7902, Wellington 6242, New Zealand.
Michaela WaltonMedical Research Institute of New Zealand, Medical Research Institute of New Zealand, Private Bag 7902, Wellington 6242, New Zealand.
Richard BeasleyMedical Research Institute of New Zealand, Medical Research Institute of New Zealand, Private Bag 7902, Wellington 6242, New Zealand.
Thomas HillsMedical Research Institute of New Zealand, Medical Research Institute of New Zealand, Private Bag 7902, Wellington 6242, New Zealand.
Medical Research Institute of New Zealand · NZCapital and Coast District Health Board · NZAuckland District Health Board · NZUniversity of Auckland · NZUniversity of Otago · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To estimate the proportion of adult diabetics with a skin to deltoid muscle distance (SDMD) of > 25 mm, representing a distance greater than the standard needle length used for intramuscular COVID-19 vaccination, and to assess whether anthropometric measurements predict ultrasound SDMD measurements. Design: Non-interventional cross-sectional study. Setting: Single site, non-clinical setting, Wellington, New Zealand. Participants: One hundred participants (50 females) aged at least 18 years diagnosis with diabetes. All participants completed the study. Main outcome measures: The proportions of participants with a SDMD > 25 mm and a SDMD > 20 mm (indicating that the needle would not have penetrated at least 5 mm into the deltoid, which is considered necessary to ensure deposition of vaccine into muscle); the relationship between anthropometric measurements (body weight, body height, body mass index (BMI), skinfold thickness, arm circumference) and SDMD measured by ultrasound. Results: The proportion (95 %CI) of participants with a SDMD > 25 mm was 6/100; 6 % (2.2 to 12.6), and the proportion with a SDMD > 20 mm was 11 % (5.6 to 18.8), of which 9/11 had a BMI ≥ 30 kg/m Conclusions: The standard needle length of 25 mm is likely to be insufficient to ensure deposition of COVID-19 vaccine within the deltoid muscle in a small but important proportion of obese adults with diabetes. Arm circumference and BMI are simple measurements that could identify those that need a long needle to ensure successful intramuscular vaccine administration. Funding: Ruth Maud Ring Spencer Estate; Health Research Council of New Zealand (Independent Research Organisation).

Indexed as

COVID-19DeltoidDiabetesNeedle lengthVaccination

Identifiers

PMID36536872
PMCPMC9753456
OpenAlexW4311549354

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.