Evidence map›Paper›PMID 36536692›Full record

ArticleJournal of molecular structure2021

Recent advances on the development of plasmon-assisted biosensors for detection of C-reactive protein.

Timea Nagy-Simon, Alexandru-Milentie Hada, Sorina Suarasan, Monica Potara

Open access · greenAbstract read
In one paragraph

Article in Journal of molecular structure, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Timea Nagy-SimonNanobiophotonics and Laser Microspectroscopy Center, Interdisciplinary Research Institute in Bio-Nano-Sciences, Babes-Bolyai University, T. Laurian 42, 400271, Cluj-Napoca, Romania.
Alexandru-Milentie HadaNanobiophotonics and Laser Microspectroscopy Center, Interdisciplinary Research Institute in Bio-Nano-Sciences, Babes-Bolyai University, T. Laurian 42, 400271, Cluj-Napoca, Romania.
Sorina SuarasanNanobiophotonics and Laser Microspectroscopy Center, Interdisciplinary Research Institute in Bio-Nano-Sciences, Babes-Bolyai University, T. Laurian 42, 400271, Cluj-Napoca, Romania.
Monica PotaraNanobiophotonics and Laser Microspectroscopy Center, Interdisciplinary Research Institute in Bio-Nano-Sciences, Babes-Bolyai University, T. Laurian 42, 400271, Cluj-Napoca, Romania.
Babeș-Bolyai University · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human C-reactive protein (CRP), an early clinical indicator of infectious or inflammatory conditions has been recently identified as a key biomarker associated with the development of COVID-19. The rapid and accurate determination of CRP level in blood serum is an urgent need to predict timely the risk of disease worsening. The emergence of nanotechnological tools has provided an attractive perspective in designing portable bioanalytical assays with fast response time, high sensitivity and specificity, and multiplexing capability for accurate, on-site disease diagnosis and monitoring. Due to their versatile optical properties, plasmonic nanoparticles (PNPs) are appealing candidates for biosensing applications. This review summarizes the advances in the application of PNPs for CRP detection and quantification. Particularly, we review the improvements attained in the detection of CRP using aggregation-based colorimetric, localized surface plasmon resonance (LSPR), plasmon-assisted fluorescence and chemiluminescence, and surface-enhanced Raman scattering (SERS) spectroscopic methods.

Indexed as

colorimetric detectionC-reactive proteinLSPRMEFplasmonic nanoparticlesSERS

Identifiers

PMID36536692
PMCPMC9749908
OpenAlexW3184497063

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.