Evidence map›Paper›PMID 36536690›Full record

Trial reportJournal of healthcare engineering2022

Development and Validation of a Prognostic Nomogram for Lung Adenocarcinoma: A Population-Based Study.

Bin Xie, Xi Chen, Qi Deng, Ke Shi, Jian Xiao, Yong Zou, Baishuang Yang, Anqi Guan, Shasha Yang, Ziyu Dai and 3 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of healthcare engineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Bin XieNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha 410008, China.ORCID 0000-0003-3685-2873
Xi ChenDepartment of Respiratory Medicine, Xiangya Hospital, Central South University, Changsha 410008, China.
Qi DengDepartment of Neurology, Xiangya Hospital, Central South University, Changsha 410008, China.ORCID 0000-0002-4226-4712
Ke ShiNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha 410008, China.
Jian XiaoNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha 410008, China.ORCID 0000-0003-2761-1779
Yong ZouDepartment of Emergency Medicine, Xiangya Hospital, Central South University, Changsha 410008, China.
Baishuang YangNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha 410008, China.ORCID 0000-0001-7473-9201
Anqi GuanNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha 410008, China.
Shasha YangNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha 410008, China.
Ziyu DaiNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha 410008, China.
Huayan XieNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha 410008, China.
Shuya HeInstitute of Biochemistry and Molecular Biology, Hengyang Medical College, University of South China, Hengyang 421001, China.
Qiong ChenNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha 410008, China.ORCID 0000-0002-2534-8834

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To establish an effective and accurate prognostic nomogram for lung adenocarcinoma (LUAD). Results: 10 prognostic factors associated with OS were identified, including age, sex, race, marital status, American Joint Committee on Cancer (AJCC) TNM stage, tumor size, grade, and primary site. A nomogram was established based on these results. C-indexes of the nomogram model reached 0.777 (95% confidence interval (CI), 0.773 to 0.781) and 0.779 (95% CI, 0.775 to 0.783) in the training and validation cohorts, respectively. The calibration curves were well-fitted for both cohorts. The AUC for the 3- and 5-year OS presented great prognostic accuracy in the training cohort (AUC = 0.832 and 0.827, respectively) and validation cohort (AUC = 0.835 and 0.828, respectively). The Kaplan-Meier curves presented significant differences in OS among the groups. Conclusion: The nomogram allows accurate and comprehensive prognostic prediction for patients with LUAD.

Indexed as

Adenocarcinoma of LungLung NeoplasmsHumansNomogramsPrognosisResearch

Identifiers

PMID36536690
PMCPMC9759395

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.