Evidence map›Paper›PMID 36536674›Full record

ArticleiScience2022

Pharmaceutical pollution disrupts the behavior and predator-prey interactions of two widespread aquatic insects.

Aneesh P H Bose, Erin S McCallum, Mladen Avramović, Michael G Bertram, Eva-Lotta Blom, Daniel Cerveny, Sara N Grønlund, Johan Leander, Petter Lundberg, Jake M Martin and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Z-Drugs in the Environment: A Review.Molecules (Basel, Switzerland) · 2026
    Review
  3. Multimodal 3D-printed passive samplers to monitor, model and prioritiseEnvironmental science. Processes & impacts · 2026
    Article
  4. Review
  5. Article
  6. Advancing the Spatiotemporal Dimension of Wildlife-Pollution Interactions.Environmental science & technology letters · 2025
    Review
  7. Review
  8. Article
  9. Article
  10. No effect of a widespread pharmaceutical pollutant on behavior, physiology, or morphology in guppies.Behavioral ecology : official journal of the International Society for Behavioral Ecology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 3 countries.

Aneesh P H BoseDepartment of Wildlife, Fish, and Environmental Studies, Swedish University of Agricultural Sciences, Skogsmarksgränd, Umeå, Västerbotten 907 36, Sweden.
Erin S McCallumDepartment of Wildlife, Fish, and Environmental Studies, Swedish University of Agricultural Sciences, Skogsmarksgränd, Umeå, Västerbotten 907 36, Sweden.
Mladen AvramovićUniversity of South Bohemia in Ceske Budejovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Zatisi 728/II, Vodnany, Czech Republic.
Michael G BertramDepartment of Wildlife, Fish, and Environmental Studies, Swedish University of Agricultural Sciences, Skogsmarksgränd, Umeå, Västerbotten 907 36, Sweden.
Eva-Lotta BlomDepartment of Wildlife, Fish, and Environmental Studies, Swedish University of Agricultural Sciences, Skogsmarksgränd, Umeå, Västerbotten 907 36, Sweden.
Daniel CervenyDepartment of Wildlife, Fish, and Environmental Studies, Swedish University of Agricultural Sciences, Skogsmarksgränd, Umeå, Västerbotten 907 36, Sweden.
Sara N GrønlundDepartment of Wildlife, Fish, and Environmental Studies, Swedish University of Agricultural Sciences, Skogsmarksgränd, Umeå, Västerbotten 907 36, Sweden.
Johan LeanderDepartment of Wildlife, Fish, and Environmental Studies, Swedish University of Agricultural Sciences, Skogsmarksgränd, Umeå, Västerbotten 907 36, Sweden.
Petter LundbergDepartment of Wildlife, Fish, and Environmental Studies, Swedish University of Agricultural Sciences, Skogsmarksgränd, Umeå, Västerbotten 907 36, Sweden.
Jake M MartinDepartment of Wildlife, Fish, and Environmental Studies, Swedish University of Agricultural Sciences, Skogsmarksgränd, Umeå, Västerbotten 907 36, Sweden.
Marcus MichelangeliDepartment of Wildlife, Fish, and Environmental Studies, Swedish University of Agricultural Sciences, Skogsmarksgränd, Umeå, Västerbotten 907 36, Sweden.
Lo PerssonDepartment of Wildlife, Fish, and Environmental Studies, Swedish University of Agricultural Sciences, Skogsmarksgränd, Umeå, Västerbotten 907 36, Sweden.
Tomas BrodinDepartment of Wildlife, Fish, and Environmental Studies, Swedish University of Agricultural Sciences, Skogsmarksgränd, Umeå, Västerbotten 907 36, Sweden.
Swedish University of Agricultural Sciences · SERoskilde University · DKUniversity of South Bohemia in České Budějovice · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pharmaceutical pollution represents a rapidly growing threat to ecosystems worldwide. Drugs are now commonly detected in the tissues of wildlife and have the potential to alter the natural expression of behavior, though relatively little is known about how pharmaceuticals impact predator-prey interactions. We conducted parallel laboratory experiments using larval odonates (dragonfly and damselfly nymphs) to investigate the effects of exposure to two pharmaceuticals, cetirizine and citalopram, and their mixture on the outcomes of predator-prey interactions. We found that exposure to both compounds elevated dragonfly activity and impacted their predation success and efficiency in complex ways. While exposure to citalopram reduced predation efficiency, exposure to cetirizine showed varied effects, with predation success being enhanced in some contexts but impaired in others. Our findings underscore the importance of evaluating pharmaceutical effects under multiple contexts and indicate that these compounds can affect predator-prey outcomes at sublethal concentrations.

Indexed as

Earth sciencesEcologyEnvironmental chemistryEnvironmental scienceNatural sciences

Identifiers

PMID36536674
PMCPMC9758520
OpenAlexW4312065336

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.