ArticleBMC infectious diseases2022
Clinical outcomes and prognostic factors of patients with sepsis caused by intra-abdominal infection in the intensive care unit: a post-hoc analysis of a prospective cohort study in Korea.
Article in BMC infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Nurse-led respiratory care bundle and pneumonia prevention in critically ill patients with abdominal sepsis: a multicenter before-and-after controlled study.Critical care (London, England) · 2026Article
- Vasopressor Use Among Adults With Sepsis in Uganda and Rwanda: A Multicenter Retrospective Cohort Study.Critical care explorations · 2026Article
- Identifying dynamic antithrombin Ⅲ trajectories to predict clinical outcomes in intra-abdominal sepsis.Journal of intensive medicine · 2026Article
- Utilizing whole genome sequencing data for machine learning driven prediction of antibiotic resistance inFrontiers in microbiology · 2026Article
- Article
- Infections and mortality in ICU patients undergoing continuous renal replacement therapy: a retrospective cohort study.BMC nephrology · 2025Article
- Damage control surgery in non-traumatic abdominal emergencies: prognostic value of SOFA, APACHEII, and Mannheim peritonitis index.Updates in surgery · 2025Article
- Microbiological profiles and clinical outcomes of critically ill surgical patients with lower gastrointestinal perforation in Japan: a single-center retrospective observational study.BMC anesthesiology · 2024Observational
- Predictive nomogram for in-hospital mortality among older patients with intra-abdominal sepsis incorporating skeletal muscle mass.Aging clinical and experimental research · 2023Article
- Sepsis among Patients Admitted to the Intensive Care Unit of a Tertiary Care Centre.JNMA; journal of the Nepal Medical Association · 2023Article
- Preoperative hypoalbuminemia as a prognosis indicator in patients with surgical sepsis and septic shock.Saudi journal of anaesthesiaArticle
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Abstract
backgroundSepsis is the most common cause of death in hospitals, and intra-abdominal infection (IAI) accounts for a large portion of the causes of sepsis. We investigated the clinical outcomes and factors influencing mortality of patients with sepsis due to IAI.
methodsThis post-hoc analysis of a prospective cohort study included 2126 patients with sepsis who visited 16 tertiary care hospitals in Korea (September 2019-February 2020). The analysis included 219 patients aged > 19 years who were admitted to intensive care units owing to sepsis caused by IAI.
resultsThe incidence of septic shock was 47% and was significantly higher in the non-survivor group (58.7% vs 42.3%, p = 0.028). The overall 28-day mortality was 28.8%. In multivariable logistic regression, after adjusting for age, sex, Charlson Comorbidity Index, and lactic acid, only coagulation dysfunction (odds ratio: 2.78 [1.47-5.23], p = 0.001) was independently associated, and after adjusting for each risk factor, only simplified acute physiology score III (SAPS 3) (p < 0.001) and continuous renal replacement therapy (CRRT) (p < 0.001) were independently associated with higher 28-day mortality.
conclusionsThe SAPS 3 score and acute kidney injury with CRRT were independently associated with increased 28-day mortality. Additional support may be needed in patients with coagulopathy than in those with other organ dysfunctions due to IAI because patients with coagulopathy had worse prognosis.
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