Evidence map›Paper›PMID 36535774›Full record

ArticleNeurology2023

Biological Sex Differences in Risk Factors and Outcomes Among Hospitalized Adults With Stroke in Lusaka, Zambia.

Aparna Nutakki, Mashina Chomba, Lorraine Chishimba Chishimba, Stanley Zimba, Rebecca F Gottesman, Mona N Bahouth, Deanna R Saylor

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 76% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Developing Systems for Cardiac and Stroke Care in Zambia.Journal of the American Heart Association · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Aparna NutakkiFrom the Rush Medical College of Rush University (A.N.), Chicago, IL; University of Zambia School of Medicine (M.C., L.C.C., D.R.S.), Lusaka; University Teaching Hospital (M.C., D.R.S.), Lusaka, Zambia; National Institute of Neurological Disorders and Stroke Intramural Research Program (R.F.G.), Bethesda, MD; Department of Neurology (D.R.S., M.N.B.), Johns Hopkins University School of Medicine, Baltimore, MD.
Mashina ChombaFrom the Rush Medical College of Rush University (A.N.), Chicago, IL; University of Zambia School of Medicine (M.C., L.C.C., D.R.S.), Lusaka; University Teaching Hospital (M.C., D.R.S.), Lusaka, Zambia; National Institute of Neurological Disorders and Stroke Intramural Research Program (R.F.G.), Bethesda, MD; Department of Neurology (D.R.S., M.N.B.), Johns Hopkins University School of Medicine, Baltimore, MD.
Lorraine Chishimba ChishimbaFrom the Rush Medical College of Rush University (A.N.), Chicago, IL; University of Zambia School of Medicine (M.C., L.C.C., D.R.S.), Lusaka; University Teaching Hospital (M.C., D.R.S.), Lusaka, Zambia; National Institute of Neurological Disorders and Stroke Intramural Research Program (R.F.G.), Bethesda, MD; Department of Neurology (D.R.S., M.N.B.), Johns Hopkins University School of Medicine, Baltimore, MD.
Stanley ZimbaFrom the Rush Medical College of Rush University (A.N.), Chicago, IL; University of Zambia School of Medicine (M.C., L.C.C., D.R.S.), Lusaka; University Teaching Hospital (M.C., D.R.S.), Lusaka, Zambia; National Institute of Neurological Disorders and Stroke Intramural Research Program (R.F.G.), Bethesda, MD; Department of Neurology (D.R.S., M.N.B.), Johns Hopkins University School of Medicine, Baltimore, MD.
Rebecca F GottesmanFrom the Rush Medical College of Rush University (A.N.), Chicago, IL; University of Zambia School of Medicine (M.C., L.C.C., D.R.S.), Lusaka; University Teaching Hospital (M.C., D.R.S.), Lusaka, Zambia; National Institute of Neurological Disorders and Stroke Intramural Research Program (R.F.G.), Bethesda, MD; Department of Neurology (D.R.S., M.N.B.), Johns Hopkins University School of Medicine, Baltimore, MD.
Mona N BahouthFrom the Rush Medical College of Rush University (A.N.), Chicago, IL; University of Zambia School of Medicine (M.C., L.C.C., D.R.S.), Lusaka; University Teaching Hospital (M.C., D.R.S.), Lusaka, Zambia; National Institute of Neurological Disorders and Stroke Intramural Research Program (R.F.G.), Bethesda, MD; Department of Neurology (D.R.S., M.N.B.), Johns Hopkins University School of Medicine, Baltimore, MD.
Deanna R SaylorFrom the Rush Medical College of Rush University (A.N.), Chicago, IL; University of Zambia School of Medicine (M.C., L.C.C., D.R.S.), Lusaka; University Teaching Hospital (M.C., D.R.S.), Lusaka, Zambia; National Institute of Neurological Disorders and Stroke Intramural Research Program (R.F.G.), Bethesda, MD; Department of Neurology (D.R.S., M.N.B.), Johns Hopkins University School of Medicine, Baltimore, MD deanna@jhmi.edu.
Johns Hopkins University · USUniversity Teaching Hospital · ZMUniversity of Zambia · ZM

Funding

UJMT – ORWH – Gazzetta, Issa-BoubeD43TW009340 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI William Checkley, Benjamin H. Chi · 2017 to 2026
$14.8M
Stroke, Cognition and Neuroepidemiology SectionZIANS009435 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI GOTTESMAN, REBECCA F · 2022 to 2025
$8.2M
Adaptation and Implementation of Clinical Practice Guidelines to Improve Stroke Outcomes in ZambiaK01TW011771 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SAYLOR, DEANNA RAE · 2021 to 2025
$1.1M
Understanding hydration and stroke outcomes in ZambiaR21NS118543 · NINDS · JOHNS HOPKINS UNIVERSITY · PI BAHOUTH, MONA N · 2020 to 2021
$354k
FIC NIH HHS D43 TW009340FIC NIH HHS K01 TW011771NINDS NIH HHS R21 NS118543
6 · The paper itself

Abstract

objectiveWe investigated sex differences in clinical characteristics and outcomes among hospitalized adults with stroke in Zambia.

methodsWe retrospectively collected information for 324 consecutively hospitalized adults with stroke on the neurology service at the University Teaching Hospital in Lusaka, Zambia, between October 2018 and March 2019. Stroke characteristics were then compared by biological sex.

resultsFemale participants constituted 62% (n = 200) of the cohort, were older (61 ± 19 vs 57 ± 16 years, DISCUSSION: Female participants in this Zambian stroke cohort had a higher prevalence of vascular risk factors but were less likely to have neuroimaging completed. Postdischarge mortality was markedly higher among female participants even after adjusting for age and stroke subtype. Our data highlight the need for future studies of social and socioeconomic factors that may influence stroke-related outcomes.

Indexed as

Sex CharacteristicsStrokeAdultAftercareFemaleHumansMalePatient DischargeRetrospective StudiesRisk FactorsSex FactorsZambia

Identifiers

PMID36535774
PMCPMC10104604
OpenAlexW4312019749

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.