Evidence map›Paper›PMID 36535690›Full record

ArticleEuropean journal of hospital pharmacy : science and practice2024

Standardisation of intravenous infusion therapy for paediatrics: big challenges for the little patients.

Irene Taladriz-Sender, Silvia Manrique-Rodríguez, Cecilia M Fernández-Llamazares, Ana Herranz-Alonso, María Sanjurjo-Sáez

Open access · greenAbstract read
In one paragraph

Article in European journal of hospital pharmacy : science and practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Irene Taladriz-SenderPharmacy, Hospital General Universitario Gregorio Maranon, Madrid, Madrid, Spain.ORCID 0000-0003-3261-6590
Silvia Manrique-RodríguezPharmacy, Hospital General Universitario Gregorio Maranon, Madrid, Madrid, Spain silvia.manrique@salud.madrid.org.
Cecilia M Fernández-LlamazaresPharmacy, Hospital General Universitario Gregorio Maranon, Madrid, Madrid, Spain.ORCID 0000-0001-6254-8715
Ana Herranz-AlonsoPharmacy, Hospital General Universitario Gregorio Maranon, Madrid, Madrid, Spain.
María Sanjurjo-SáezPharmacy, Hospital General Universitario Gregorio Maranon, Madrid, Madrid, Spain.
Hospital General Universitario Gregorio Marañón · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWorldwide organisations advocate standardising the management of intravenous drugs as an essential strategy to increase safety in paediatric healthcare settings. Intravenous administration is a route associated with some potential complications. Many adverse events are related to the use of intravenous medications, and the great variability in their handling and preparation represents an added risk that jeopardises the safety of children. PURPOSE: To standardise the dilutions of intravenous drugs most commonly administered to Spanish hospitalised paediatric and neonatal patients.

methodsThe process leading to the standardisation of concentrations was undertaken following a two-round modified Delphi procedure. The consensus included the most common drugs administered by continuous or intermittent intravenous infusion to hospitalised and/or critically ill paediatric patients.

resultsFor paediatric patients, the proposal included a total of 102 drugs (45 continuous infusion and 59 intermittent infusion), with 192 concentrations to be standardised. The final consensus included 101 drugs (99%), of which 44 were continuous infusion and 59 intermittent infusion; 160 concentrations were standardised (72.7%). For neonates, the initial proposal included 80 drugs (38 continuous infusion and 43 intermittent infusion), with 189 concentrations to be standardised. The final consensus included 80 drugs (100%), of which 38 were continuous infusion and 43 were intermittent infusion; 120 concentrations were standardised (49.2%).

conclusionsThis proposal showed that standardisation is a feasible approach that can be reached by other healthcare institutions. It can be used in other centres and contribute in the future to unifying paediatric clinical practice.

Indexed as

Delphi TechniqueChildChild, PreschoolConsensusHumansInfantInfant, NewbornInfusions, IntravenousPediatricsPharmaceutical PreparationsSpainPharmaceutical PreparationsAdministration, IntravenousNEONATOLOGYPEDIATRICSPHARMACEUTICAL PREPARATIONSSafety

Identifiers

PMID36535690
PMCPMC11042264
OpenAlexW4311943330

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.