Evidence map›Paper›PMID 36535439›Full record

ArticleThe Journal of arthroplasty2023

Primary and Revision Total Hip Arthroplasty in Patients With Pulmonary Hypertension: High Perioperative Mortality and Medical Complications.

Courtney E Baker, Brian P Chalmers, Michael J Taunton, Adam W Amundson, Daniel J Berry, Matthew P Abdel

Open access · greenAbstract read
In one paragraph

Article in The Journal of arthroplasty, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Courtney E BakerDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.
Brian P ChalmersDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.
Michael J TauntonDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.
Adam W AmundsonDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota.
Daniel J BerryDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.
Matthew P AbdelDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.
Mayo Clinic · US

Funding

Resource CoreP30AR076312 · NIAMS · MAYO CLINIC ROCHESTER · PI Daniel Berry · 2019 to 2026
$5.5M
Precision Orthopedics: Multimodal Data Infrastructure for Personalized Surgical Decisions in Joint ArthroplastyR01AR073147 · NIAMS · MAYO CLINIC ROCHESTER · PI Hilal Maradit Kremers · 2018 to 2026
$3.5M
Cardiotoxicity in Total Joint ArthroplastyR01HL147155 · NHLBI · MAYO CLINIC ROCHESTER · PI MARADIT KREMERS, HILAL · 2019 to 2022
$2.8M
NHLBI NIH HHS R01 HL147155NIAMS NIH HHS P30 AR076312NIAMS NIH HHS R01 AR073147
6 · The paper itself

Abstract

backgroundPerioperative medical management during total hip arthroplasty (THA) is continuously improving, allowing an increasing number of medically complex patients to undergo total joint arthroplasty. This study examined mortalities, medical complications, implant survivorships, and clinical outcomes of THA in patients who have pulmonary hypertension (HTN).

methodsWe identified 638 patients who had pulmonary HTN and underwent 508 primary THAs and 191 revision THAs from 2000 to 2016 at a tertiary care center. Patients were followed up at regular intervals until death, revision surgery, or last clinical follow-up. Perioperative medical complications were individually reviewed. The risk of death was examined by calculating standardized mortality ratios and Cox proportional hazards regression models. Cumulative incidence analyses were used for reporting mortality, reoperation, and revision with death as a competing risk.

resultsThe 90-day mortality was 1.8% and 3.1% for primary and revision THAs, respectively. The risk of death was approximately two-fold higher compared to primary (hazard ratio 2.69) and revision (hazard ratio 2.04) THA patients who did not have pulmonary HTN. Rate of medical complications within 90 days from surgery were 6.2% and 13.1% in primary and revision THAs, respectively. The 10-year cumulative incidence of any revision was 9% and 14% following primaries and revisions, respectively.

conclusionPatients who had pulmonary HTN undergoing primary and revision THAs had an increased risk of death and experienced a high rate of medical complications within 90 days of surgery. Counseling of risks, medical optimization, and referral to medical centers expert at managing complex medical problems should be considered. LEVEL OF EVIDENCE: Level IV.

Indexed as

Arthroplasty, Replacement, HipHip ProsthesisHypertension, PulmonaryHumansRegistriesReoperationRisk Factorscomplicationsmortalitypulmonary hypertensionrevision total hip arthroplastytotal hip arthroplasty

Identifiers

PMID36535439
PMCPMC10430475
OpenAlexW4311888778

What OpenQuestion holds

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LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.