Evidence map›Paper›PMID 36535326›Full record

ArticleNature2023

Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution.

Yunlong Cao, Fanchong Jian, Jing Wang, Yuanling Yu, Weiliang Song, Ayijiang Yisimayi, Jing Wang, Ran An, Xiaosu Chen, Na Zhang and 16 more

Abstract read
In one paragraph

Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 552 papers.

0numbers the graph read from it
0cells of the map it votes in
552citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

552 citing papers in PubMed.

  1. Trial
  2. Ensitrelvir for the Treatment of Nonhospitalized Adults with COVID-19: Results from the SCORPIO-HR, Phase 3, Randomized, Double-blind, Placebo-Controlled Trial.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
    Trial
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492 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Yunlong Cao *Biomedical Pioneering Innovation Center (BIOPIC), Peking University, Beijing, P. R. China. yunlongcao@pku.edu.cn.ORCID 0000-0001-5918-1078
Fanchong Jian *Biomedical Pioneering Innovation Center (BIOPIC), Peking University, Beijing, P. R. China.ORCID 0000-0001-8703-3507
Jing Wang *Biomedical Pioneering Innovation Center (BIOPIC), Peking University, Beijing, P. R. China.ORCID 0000-0002-9084-9985
Yuanling Yu *Changping Laboratory, Beijing, P. R. China.
Weiliang Song *Biomedical Pioneering Innovation Center (BIOPIC), Peking University, Beijing, P. R. China.
Ayijiang YisimayiBiomedical Pioneering Innovation Center (BIOPIC), Peking University, Beijing, P. R. China.
Jing WangChangping Laboratory, Beijing, P. R. China.
Ran AnChangping Laboratory, Beijing, P. R. China.
Xiaosu ChenInstitute for Immunology, College of Life Sciences, Nankai University, Tianjin, P. R. China.
Na ZhangChangping Laboratory, Beijing, P. R. China.
Yao WangChangping Laboratory, Beijing, P. R. China.
Peng WangChangping Laboratory, Beijing, P. R. China.
Lijuan ZhaoChangping Laboratory, Beijing, P. R. China.
Haiyan SunChangping Laboratory, Beijing, P. R. China.
Lingling YuChangping Laboratory, Beijing, P. R. China.
Sijie YangBiomedical Pioneering Innovation Center (BIOPIC), Peking University, Beijing, P. R. China.
Xiao NiuBiomedical Pioneering Innovation Center (BIOPIC), Peking University, Beijing, P. R. China.
Tianhe XiaoBiomedical Pioneering Innovation Center (BIOPIC), Peking University, Beijing, P. R. China.
Qingqing GuChangping Laboratory, Beijing, P. R. China.ORCID 0000-0001-5805-6419
Fei ShaoChangping Laboratory, Beijing, P. R. China.
Xiaohua HaoBeijing Ditan Hospital, Capital Medical University, Beijing, P. R. China.
Yanli XuBeijing Ditan Hospital, Capital Medical University, Beijing, P. R. China.
Ronghua JinBeijing Ditan Hospital, Capital Medical University, Beijing, P. R. China.ORCID 0000-0001-8496-172X
Zhongyang ShenOrgan Transplant Center, NHC Key Laboratory for Critical Care Medicine, Tianjin First Central Hospital, Nankai University, Tianjin, P. R. China.ORCID 0000-0003-0045-4355
Youchun WangChangping Laboratory, Beijing, P. R. China. wangyc@nifdc.org.cn.ORCID 0000-0001-9769-5141
Xiaoliang Sunney XieBiomedical Pioneering Innovation Center (BIOPIC), Peking University, Beijing, P. R. China. sunneyxie@biopic.pku.edu.cn.ORCID 0000-0001-9281-5239

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Continuous evolution of Omicron has led to a rapid and simultaneous emergence of numerous variants that display growth advantages over BA.5 (ref.

Indexed as

Antibodies, ViralAntigenic Drift and ShiftCOVID-19Evolution, MolecularImmunity, HumoralSARS-CoV-2Spike Glycoprotein, CoronavirusAngiotensin-Converting Enzyme 2Antibodies, MonoclonalAntibodies, NeutralizingBreakthrough InfectionsCOVID-19 SerotherapyCOVID-19 VaccinesHumansImmunization, SecondaryMutationACE2 protein, humanAngiotensin-Converting Enzyme 2Antibodies, MonoclonalAntibodies, NeutralizingAntibodies, ViralCOVID-19 VaccinesSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2

Identifiers

PMID36535326
PMCPMC9931576

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.