Evidence map›Paper›PMID 36535230›Full record

ArticleSocial science & medicine (1982)2023

"Letting go" - Relinquishing control of illness outcomes to God and quality of life: Meaning/peace as a mediating mechanism in religious coping with cancer.

Thomas V Merluzzi, Natalia Salamanca-Balen, Errol J Philip, John M Salsman

Abstract read
In one paragraph

Article in Social science & medicine (1982), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Acceptance in Patients With Cancer: A Scoping Review.Cancer reports (Hoboken, N.J.) · 2025
    Article
  7. Article
  8. Observational
  9. Review
  10. Review
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

4 authors.

Thomas V MerluzziUniversity of Notre Dame, Department of Psychology, United States. Electronic address: tmerluzz@nd.edu.
Natalia Salamanca-BalenUniversity of Notre Dame, Department of Psychology, United States.
Errol J PhilipUniversity of Notre Dame, Department of Psychology, United States.
John M SalsmanWake Forest University College of Medicine, Social Sciences and Health Policy, United States.

Funding

Cultural Analysis of the Cancer Behavior InventoryR21CA094914 · NCI · UNIVERSITY OF NOTRE DAME · PI MERLUZZI, THOMAS V · 2005 to 2006
$319k
NCI NIH HHS R21 CA094914
6 · The paper itself

Abstract

backgroundRelinquishing control (RC) of outcomes to God is a long-standing form of religious coping with serious illness. Placing cancer outcomes "in God's hands" has been positively related to coping and quality of life (QOL). However, the mechanisms involved in this relationship have not been established. A serial mediation model [i.e., RC (X)-Meaning/Peace (M1)-Coping Efficacy (M2)-Symptoms, Physical QOL, Functional QOL (Ys)] tested the hypothesis that Meaning/Peace alone and in conjunction with coping would mediate the RC-QOL relationship.

method548 persons with a cancer diagnosis completed the Religious Problem-Solving Scale (RPSS), FACIT-Sp Meaning and Peace Scales, Cancer Behavior Inventory (coping efficacy), and measures of Physical Quality of Life (PQOL), Functional Quality of Life (FQOL) and Symptoms.

resultsAs hypothesized, the single mediation effects of Meaning/Peace were significant [Indirect Effects: PQOL: .23 (95% CI: 0.15, 0.34); FQOL: 0.46 (95% CI: 0.33, 0.61); Symptoms: -0.18 (95% CI: -0.27, -0.10)]. In addition, mediation was confirmed for the serial mediation model (i.e., Meaning/Peace - Coping Efficacy as serial mediators) with significant indirect effects [Indirect Effects: PQOL: 0.37 (95% CI: 0.27, 0.48); FQOL: 0.57 (95% CI: 0.42, 0.72); Symptoms: -0.25 (95% CI: -0.35, -0.17)].

conclusionsIn the mediation models tested, the RC-QOL and RC-Symptoms relationships were mediated by the confluence of a sense of peace perhaps due to patients' feelings that outcomes were "in God's hands" and a sense of coherence between their current situation and a spiritually-based meaning system. Meaning/Peace was also related to coping efficacy, suggesting that these mediating constructs could be used to inform evidence-based interventions, such as Meaning-Centered therapies, that are sensitive to the belief systems of cancer patients and enhance QOL.

Indexed as

NeoplasmsQuality of LifeAdaptation, PsychologicalHumansSocial ConditionsSpiritualityCancerCopingLetting go”Quality of lifeReligionRelinquishing controlSpirituality

Identifiers

PMID36535230
PMCPMC9962851

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.