Evidence map›Paper›PMID 36534333›Full record

ArticleBiochemical genetics2023

In Silico Genome-Wide Mining and Analysis of Terpene Synthase Gene Family in Hevea Brasiliensis.

Jiahao Liang, De Wang, Xin Li, Weiwen Huang, Chun Xie, Minghui Fu, Hongmei Zhang, Qiong Meng

Abstract read
PubMed Publisher
In one paragraph

Article in Biochemical genetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jiahao LiangSchool of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, No.100 Waihuan Xi Road, Guangzhou, 510006, China.
De WangSchool of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, No.100 Waihuan Xi Road, Guangzhou, 510006, China.
Xin LiSchool of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, No.100 Waihuan Xi Road, Guangzhou, 510006, China.
Weiwen HuangSchool of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, No.100 Waihuan Xi Road, Guangzhou, 510006, China.
Chun XieSchool of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, No.100 Waihuan Xi Road, Guangzhou, 510006, China.
Minghui FuSchool of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, No.100 Waihuan Xi Road, Guangzhou, 510006, China. mhfugd@126.com.
Hongmei ZhangSchool of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, No.100 Waihuan Xi Road, Guangzhou, 510006, China.
Qiong MengGuangdong Second Provincial General Hospital, No.466 Xingang Zhong Road, Guangzhou, 510006, China.
Guangdong University of Technology · CNGuangdong Provincial People's Hospital · CN

Funding

Guangzhou Municipal Science and Technology Project 201903010025Science and Technology Planning Project of Guangdong Province 2016A010105020
6 · The paper itself

Abstract

Terpene synthases (TPSs) catalyze terpenoid synthesis and affect the intracellular isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) concentration. In this study, we mined the in silico genome-wide TPS genes of Hevea brasiliensis and identified 47 full-length TPS genes. They had DDXXD, DXDD, NSE/DTE, RR(X)8 W, EA(X)W, and other conserved motifs. The phylogenetic tree analysis revealed that the TPSs of H.brasiliensis (HbTPSs) were divided into five subfamilies, TPS-a, TPS-b, TPS-c, TPS-e/f, and TPS-g. HbTPSs were predicted to have functions in the cellular components, molecular functions, and biological processes. HbTPSs were involved in seven pathways, which were K14173, K14175, K15803, K04120, K04121, K17982, and K12742 in the secondary metabolite pathway prediction. Three-dimensional structures of HbTPSs of 7 pathways were predicted, and DDXXD, NSE/DTE, and EA(X)W conserved motifs near the binding sites were found. Cis-acting elements analysis showed that they had more cis-acting elements related to phytohormone responsiveness, which indicated that terpenoid biosynthesis might be related to phytohormone regulation. RNA-Seq analysis showed that different HbTPSs were expressed differentially in different tissues. This study's results help reveal the role of HbTPSs and their molecular mechanism and help resolve the regulatory mechanism of terpenoid biosynthesis in H.brasiliensis.

Indexed as

Alkyl and Aryl TransferasesHeveaHemiterpenesOrganophosphorus CompoundsPhylogenyPlant Growth RegulatorsPlant Proteins3,3-dimethylallyl pyrophosphateAlkyl and Aryl TransferasesHemiterpenesOrganophosphorus CompoundsPlant Growth RegulatorsPlant Proteinsterpene synthaseAnalysisGenome-wideHevea brasiliensisIn silicoMiningTerpene synthase

Identifiers

PMID36534333
OpenAlexW4311933080

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.