SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2022
Effects of prehabilitation on postoperative outcomes in frail cancer patients undergoing elective surgery: a systematic review and meta-analysis.
Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07390071 (Multimodal Telerehabilitation in Patients Undergoing CAR-T Cell Immunotherapy), which is not on this map. Cited by 30 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Multimodal Telerehabilitation in Patients Undergoing CAR-T Cell Immunotherapy
Who cites it
30 citing papers in PubMed, 7 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Effectiveness of exercise interventions on functional outcomes in frail adults with a previous or current diagnosis of cancer: a systematic review and meta-analysis.Journal of cancer survivorship : research and practice · 2026Pooled it
- Frailty assessment and effect of physical activity interventions in older adults: a scoping review, meta-analysis, and meta-regression.BMC geriatrics · 2026Pooled it
- Prehabilitation in Frail Patients Undergoing Cancer Surgery: A Systematic Review and Meta-analysis.Annals of surgical oncology · 2025Pooled it
- Physical Prehabilitation for Older Patients with Cancer before Complex Medical-Surgical Interventions: An Umbrella Review.Aging and disease · 2024Pooled it
- Pooled it
- The use of technology in cancer prehabilitation: a systematic review.Frontiers in oncology · 2024Pooled it
- Effects of unimodal or multimodal prehabilitation on patients undergoing surgery for esophagogastric cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Pooled it
- Trial
- Prehabilitation Prior to Colorectal Cancer Surgery: Impact and Implementation.Journal of surgical oncology · 2026Article
- Review
- Prehabilitation in older adults with cancer: scoping review of surgical outcomes.BMJ supportive & palliative care · 2026Article
- Multimodal prehabilitation for frail older adults having hip or knee replacement: a qualitative exploratory study of barriers and facilitators.BMC musculoskeletal disorders · 2026Article
- The Impact of Malnutrition and Multimodal Prehabilitation on Quality of Life in Head and Neck Cancer Patients Following Resection and Microvascular Reconstruction: A Cross-Sectional Study.Journal of clinical medicine · 2026Article
- Surgery in Older Cancer Patients.Current oncology reports · 2026Review
- Perioperative nutrition-oriented nursing for older women undergoing cancer surgery: frailty screening, enhanced recovery, and survivorship care.Frontiers in public health · 2026Review
- Adherence to Exercise Training Within a Multimodal Prehabilitation Program: An Exploratory Study of Influencing Factors.Journal of clinical medicine · 2025Article
- Perspectives on prehabilitation for older adults with cancer: A report from the International Society of Geriatric Oncology (SIOG) rehabilitation group.Journal of geriatric oncology · 2025Article
- Article
- The pervasive impact of frailty on ovarian cancer care and the role of prehabilitation: Qualitative perspectives of key stakeholders.Journal of geriatric oncology · 2025Article
- Effects of a Tele-Prehabilitation Program with Indirect Electrostimulation Compared to Home-Based Exercise in Patients Eligible for Lower Limb Arthroplasty: A Randomized Controlled Trial.Journal of clinical medicine · 2025Article
Corrections and comments
- Commented on by
Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
Abstract
purposeThis systematic review and meta-analys is aimed to explore the effects of prehabilitation on postoperative outcomes in frail cancer patients.
methodsA comprehensive literature search was conducted using PubMed, Cochrane Library, Embase, Web of Science, CINAHL Complete, and other databases from database inception to 15 March 2022. Studies were included if they consisted of a prehabilitation intervention in frail cancer patients undergoing elective surgery.
resultsA total of 9 studies encompassing 1313 patients were included in the review. Through meta-analysis, prehabilitation has a positive impact on total complications (RR = 0.83, 95% CI = 0.73 to 0.94, P = 0.004), severe complications (RR = 0.62, 95% CI = 0.43 to 0.90, P = 0.01), and the average length of hospital stay (MD = - 1.36, 95% CI = - 2.38 to - 0.35, P = 0.008). But it had no differences in 30-day and 3-month mortality and 30-day and 3-month readmission rates. Through qualitative synthesis, two studies found that prehabilitation had a favorable tendency to promote functional recovery compared with the control group.
conclusionPrehabilitation had a positive effect on postoperative complications and the average length of hospital stay in frail cancer patients. A personalized and supervised multimodal prehabilitation program with exercise at its core may be more beneficial for them. More studies with extensive follow-up are needed to confirm and update the findings of these results.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.