Evidence map›Paper›PMID 36534232›Full record

ArticlePflugers Archiv : European journal of physiology2023

Synergistic effects of agonists and two-pore-domain potassium channels on secretory responses of human pancreatic duct cells Capan-1.

Christiane E Sørensen, Anna Trauzold, Nynne M Christensen, Doaa Tawfik, Monika Szczepanowski, Ivana Novak

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Mechanism ofFrontiers in microbiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Christiane E SørensenSection for Cell Biology and Physiology, Department of Biology, University of Copenhagen, Copenhagen, Denmark. ches@sund.ku.dk.
Anna TrauzoldInstitute for Experimental Cancer Research, University of Kiel, Kiel, Germany.
Nynne M ChristensenSection for Cell Biology and Physiology, Department of Biology, University of Copenhagen, Copenhagen, Denmark.
Doaa TawfikInstitute for Experimental Cancer Research, University of Kiel, Kiel, Germany.
Monika SzczepanowskiDepartment of Pathology Hematopathology Section and Lymph Node Registry, University Hospital Schleswig-Holstein, Kiel, Germany.
Ivana NovakSection for Cell Biology and Physiology, Department of Biology, University of Copenhagen, Copenhagen, Denmark.
University of Copenhagen · DKCairo University · EGUniversity Hospital Schleswig-Holstein · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mechanisms of synergistic agonist stimulation and modulation of the electrochemical driving force for anion secretion are still not fully explored in human pancreatic duct epithelial cells. The first objective of this study was therefore to test whether combined agonist stimulation augments anion transport responses in the Capan-1 monolayer model of human pancreatic duct epithelium. The second objective was to test the influence of H

Indexed as

AdenocarcinomaPancreatic NeoplasmsAdenosine TriphosphatasesBicarbonatesEpithelial CellsHumansPancreatic DuctsRNA, MessengerAdenosine TriphosphatasesBicarbonatesRNA, MessengerHistamineH+,K+-ATPaseK2P channelsOmeprazolePancreasRiluzole

Identifiers

PMID36534232
PMCPMC9908661
OpenAlexW4311929443

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.