Evidence map›Paper›PMID 36534195›Full record

ReviewAnnals of intensive care2022

Sex and out-of-hospital cardiac arrest survival: a systematic review.

Ines Lakbar, Mariachiara Ippolito, Aviv Nassiri, Louis Delamarre, Philippe Tadger, Marc Leone, Sharon Einav

Open access · goldAbstract readReview
In one paragraph

Review in Annals of intensive care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 25 citations in OpenAlex.

  1. The missing sex and gender lens in artificial-intelligence-enabled resuscitation.Scandinavian journal of trauma, resuscitation and emergency medicine · 2026
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  2. Observational
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  4. Observational
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  7. Sex differences in out-of-hospital cardiac arrest.European heart journal open · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 4 countries.

Ines LakbarAix-Marseille University, Publique Hôpitaux de Marseille, Marseille, France. ines.lakbar@ap-hm.fr.ORCID http://orcid.org/0000-0003-0049-6248
Mariachiara IppolitoDepartment of Surgical, Oncological and Oral Science (Di.Chir.On.S.), University of Palermo, Palermo, Italy.
Aviv NassiriDepartment of Military Medicine and Tzameret, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
Louis DelamarreAix-Marseille University, Publique Hôpitaux de Marseille, Marseille, France.
Philippe TadgerReal World Evidence, IQVIA, 3600, Genk, Belgium.
Marc LeoneAix-Marseille University, Publique Hôpitaux de Marseille, Marseille, France.
Sharon EinavIntensive Care Unit, Shaare Zedek Medical Center, Jerusalem, Israel.
Ceres · USAix-Marseille Université · FRAzienda Ospedaliera Universitaria Policlinico "Paolo Giaccone" di Palermo · ITHebrew University of Jerusalem · ILShaare Zedek Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe literature is unresolved on whether female receive advanced cardiac life support less than do male and on whether female have a survival advantage over male after cardiopulmonary resuscitation.

methodsWe systematically searched PubMed, Embase and Web of Science databases (from inception to 23-April-2022) for papers reporting outcomes in adult male and female after out-of-hospital cardiac arrest. The main study outcome was the rate of adjusted survival to hospital discharge or 30 days. Secondary outcomes included unadjusted survival to hospital discharge and favourable neurological outcome.

resultsA total of 28 studies were included, involving 1,931,123 patients. Female were older than male, their cardiac arrests were less likely to be witnessed and less likely to present with a shockable rhythm. Unadjusted analysis showed that females had a lower likelihood of survival than males (OR 0.68 [0.62-0.74], I

conclusionsThe adjusted rate of survival to hospital discharge/30 days was similar for male and female despite an initial seeming survival advantage for male. The validity of this finding is limited by substantial heterogeneity despite in-depth investigation of its causes, which raises concerns regarding latent inequalities in some reports nonetheless. Further study on this topic may require inclusion of factors not reported in the Utstein template and in-depth analysis of decision-making processes.

Indexed as

Gender disparitiesOutcomesOut-of-hospital cardiac arrestSex

Identifiers

PMID36534195
PMCPMC9763524
OpenAlexW4312095091

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.