Evidence map›Paper›PMID 36534193›Full record

Observational studyNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2023

A gait-based paradigm to investigate central body representation in cervical dystonia patients.

O Crisafulli, E Ravizzotti, S Mezzarobba, C Cosentino, G Bonassi, A Botta, G Abbruzzese, R Marchese, L Avanzino, E Pelosin

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

O CrisafulliDepartment of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy.
E RavizzottiDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics and Maternal Child Health (DINOGMI), University of Genoa, Largo P. Daneo 3, 16132, Rehabilitation Genoa, Ophthalmology, Italy.
S MezzarobbaDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics and Maternal Child Health (DINOGMI), University of Genoa, Largo P. Daneo 3, 16132, Rehabilitation Genoa, Ophthalmology, Italy.
C CosentinoDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics and Maternal Child Health (DINOGMI), University of Genoa, Largo P. Daneo 3, 16132, Rehabilitation Genoa, Ophthalmology, Italy.
G BonassiS.C. Medicina Fisica e Riabilitazione Ospedaliera, Azienda Sanitaria Locale Chiavarese, 16043, Chiavari, Italy.
A BottaIRCCS Ospedale Policlinico San Martino, Genoa, Italy.
G AbbruzzeseDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics and Maternal Child Health (DINOGMI), University of Genoa, Largo P. Daneo 3, 16132, Rehabilitation Genoa, Ophthalmology, Italy.
R MarcheseIRCCS Ospedale Policlinico San Martino, Genoa, Italy.
L AvanzinoIRCCS Ospedale Policlinico San Martino, Genoa, Italy.
E PelosinDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics and Maternal Child Health (DINOGMI), University of Genoa, Largo P. Daneo 3, 16132, Rehabilitation Genoa, Ophthalmology, Italy. elisa.pelosin@unige.it.ORCID http://orcid.org/0000-0002-9880-2241
Ospedale Policlinico San Martino · ITUniversity of Genoa · ITASL Roma · ITUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCervical dystonia (CD) is a common adult-onset idiopathic form of dystonia characterized by an abnormal head posture caused by an excessive activity of the neck muscles. The position of the head is important to direct viewpoint in the rounding environment, and the body orientation, during gait, must be coherent with the subjective straight ahead (SSA). An alteration of the SSA, as in the case of CD patients, could affect gait when visual input is not available. The aim of this study was to probe the behavior of patients with CD during blindfolded walking, investigating the ability to walk straight ahead based only on somatosensory and vestibular information.

methodsIn this observational cross-sectional study, patients with CD and healthy control subjects (HC) were compared. All participants were evaluated through a gait analysis during blindfolded walking on a GAITRite carpet, relying on their own sense of straightness.

resultsPatients with CD showed lower values of path length (p < 0.001), a lower number of steps on the carpet (p < 0.001). A higher number of CD patients deviated during the task, walking out of the carpet, (p < 0.005) compared to HS. No relation was found between the dystonic side and the gait trajectory deviation. A significant correlation was found between pain symptom and gait performance.

conclusionsCD patients showed dysfunctions in controlling dynamic body location during walking without visual afferences, while the dystonic side does not seem to be related to the lateral deviation of the trajectory. Our results would assume that a general proprioceptive impairment could lead to an improper body position awareness in patients with CD.

Indexed as

TorticollisAdultBody ImageGaitHumansNeck MusclesWalkingBody representationCervical dystoniaProprioception, Blindfolded gait

Identifiers

PMID36534193
OpenAlexW4311927814

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.