Evidence map›Paper›PMID 36533950›Full record

ArticleJournal of virology2023

Activity, Template Preference, and Compatibility of Components of RNA Replicase of Eastern Equine Encephalitis Virus.

Laura Sandra Lello, Agneta Miilimäe, Liubov Cherkashchenko, Ailar Omler, Rachel Skilton, Rachel Ireland, David Ulaeto, Andres Merits

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Laura Sandra LelloInstitute of Technology, University of Tartu, Tartu, Estonia.
Agneta MiilimäeInstitute of Technology, University of Tartu, Tartu, Estonia.
Liubov CherkashchenkoInstitute of Technology, University of Tartu, Tartu, Estonia.
Ailar OmlerInstitute of Technology, University of Tartu, Tartu, Estonia.
Rachel SkiltonCBR Division, Dstl Porton Down, Salisbury, UK.
Rachel IrelandCBR Division, Dstl Porton Down, Salisbury, UK.
David UlaetoCBR Division, Dstl Porton Down, Salisbury, UK.
Andres MeritsInstitute of Technology, University of Tartu, Tartu, Estonia.ORCID 0000-0001-8193-0071
University of Tartu · EEDefence Science and Technology Laboratory · GB

Funding

Medical Research Council MC_PC_16028Wellcome Trust 200171/Z/15/Z
6 · The paper itself

Abstract

Eastern equine encephalitis virus (EEEV) usually cycles between Culiseta melanura mosquitoes and birds; however, it can also infect humans. EEEV has a positive-sense RNA genome that, in infected cells, serves as an mRNA for the P1234 polyprotein. P1234 undergoes a series of precise cleavage events producing four nonstructural proteins (nsP1-4) representing subunits of the RNA replicase. Here, we report the construction and properties of a

Indexed as

Chikungunya virusEncephalitis Virus, Eastern EquineRNA-Dependent RNA PolymeraseViral Nonstructural ProteinsAnimalsHEK293 CellsHorsesHumansRNA, ViralVirus ReplicationRNA-Dependent RNA PolymeraseRNA, ViralViral Nonstructural ProteinsalpavirusEEEVRNA replicaseRNA replicationtemplate RNA

Identifiers

PMID36533950
PMCPMC9888243
OpenAlexW4311927092

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.