Evidence map›Paper›PMID 36533947›Full record

ArticleMicrobiology spectrum2023

Microbiome-Metabolomics Analysis of the Impacts of

Luyang Wang, Letian Cao, Yankai Chang, Yin Fu, Yuexin Wang, Kaihui Zhang, Sumei Zhang, Longxian Zhang

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
9.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Emergence of zoonoticFrontiers in microbiology · 2026
    Article
  4. Review
  5. Current research in parasitology & vector-borne diseases · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Frontiers in microbiology · 2023
    Article
  12. Article
  13. Tropical parasitology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Luyang WangCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China.ORCID 0000-0002-6103-3821
Letian CaoCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China.
Yankai ChangCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China.
Yin FuCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China.
Yuexin WangCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China.
Kaihui ZhangCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China.
Sumei ZhangCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China.
Longxian ZhangCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China.ORCID 0000-0001-9310-1975
Ministry of Agriculture and Rural Affairs · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cryptosporidium is a leading cause of diarrheal disease and mortality in young children worldwide. Cryptosporidium invades small intestinal epithelial cells and forms a unique intracellular niche, a process that may alter gut microbes and their production metabolites. However, the mechanism of interactions between gut microbes, metabolites, and parasites is poorly understood. Here, we first characterized the impacts of Cryptosporidium infection on gut microbiota using a microbiome-to-metabolome association study. BALB/c mice were gavaged with Cryptosporidium muris, and fecal samples were collected at 0, 7, 14, 21, and 28 days postinfection (dpi) to observe changes in the intestinal microbes of the body during parasite infection. The infected group had a significantly increased relative abundance of bacterial taxa, such as

Indexed as

CryptosporidiosisCryptosporidiumMicrobiotaAnimalsBile Acids and SaltsChildChild, PreschoolFatty Acids, VolatileFecesHumansMetabolomeMetabolomicsMiceMice, Inbred BALB CBile Acids and SaltsFatty Acids, Volatilebile acidCryptosporidiumgut microbiotametabolitesshort-chain fatty acid

Identifiers

PMID36533947
PMCPMC9927150
OpenAlexW4311934896

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.