Evidence map›Paper›PMID 36533920›Full record

ArticleThe Analyst2023

Isobaric 6-plex and tosyl dual tagging for the determination of positional isomers and quantitation of monounsaturated fatty acids using rapid UHPLC-MS/MS.

Michael R Armbruster, Mahmoud Elhusseiny Mostafa, Rhea N Caldwell, Scott F Grady, Christopher K Arnatt, James L Edwards

Open access · greenAbstract read
In one paragraph

Article in The Analyst, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Aziridination-Enabled Structural and Quantitative Lipidomics.Journal of the American Society for Mass Spectrometry · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Dual Fragmentation Isobaric Tags for Metabolomics.Journal of the American Society for Mass Spectrometry · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Michael R ArmbrusterDepartment of Chemistry and Biochemistry, Saint Louis University, 3501 Laclede Ave, St. Louis, MO, 63103, USA. jim.edwards@slu.edu.ORCID http://orcid.org/0000-0002-9453-3419
Mahmoud Elhusseiny MostafaDepartment of Chemistry and Biochemistry, Saint Louis University, 3501 Laclede Ave, St. Louis, MO, 63103, USA. jim.edwards@slu.edu.ORCID http://orcid.org/0000-0001-7688-1789
Rhea N CaldwellDepartment of Chemistry and Biochemistry, Saint Louis University, 3501 Laclede Ave, St. Louis, MO, 63103, USA. jim.edwards@slu.edu.
Scott F GradyDepartment of Chemistry and Biochemistry, Saint Louis University, 3501 Laclede Ave, St. Louis, MO, 63103, USA. jim.edwards@slu.edu.
Christopher K ArnattDepartment of Chemistry and Biochemistry, Saint Louis University, 3501 Laclede Ave, St. Louis, MO, 63103, USA. jim.edwards@slu.edu.
James L EdwardsDepartment of Chemistry and Biochemistry, Saint Louis University, 3501 Laclede Ave, St. Louis, MO, 63103, USA. jim.edwards@slu.edu.ORCID http://orcid.org/0000-0003-1063-7518
Saint Louis University · US

Funding

Universal Metabolite TaggingR01GM134081 · NIGMS · SAINT LOUIS UNIVERSITY · PI ARNATT, CHRISTOPHER K, BYTHELL, BENJAMIN J. · 2019 to 2022
$1.8M
NIGMS NIH HHS R01 GM134081
6 · The paper itself

Abstract

Isobaric labelling of fatty acids is complicated by chromatographic co-elution of double bond isomers. This produces contaminated spectra which can mask important biological changes. Here two derivatization strategies are combined to improve throughput and produce MS

Indexed as

Fatty Acids, MonounsaturatedTandem Mass SpectrometryChromatography, High Pressure LiquidFatty AcidsIsomerismFatty AcidsFatty Acids, Monounsaturated

Identifiers

PMID36533920
PMCPMC12711191
OpenAlexW4311526171

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.