Evidence map›Paper›PMID 36533629›Full record

ReviewEMBO reports2023

Fighting antibiotic resistance-strategies and (pre)clinical developments to find new antibacterials.

Sebastian Walesch, Joy Birkelbach, Gwenaëlle Jézéquel, F P Jake Haeckl, Julian D Hegemann, Thomas Hesterkamp, Anna K H Hirsch, Peter Hammann, Rolf Müller

Abstract readReview
In one paragraph

Review in EMBO reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed.

  1. Drug-likeness prioritised selection identifies anti-Journal of enzyme inhibition and medicinal chemistry · 2026
    Article
  2. Article
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  4. Collective fluctuations underlying nanobody inhibitory activity targetingbioRxiv : the preprint server for biology · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Identification of Natural-Product Inhibitors of the 2ACS medicinal chemistry letters · 2026
    Article
  11. Article
  12. Article
  13. Bacterial cell envelope-targeting antibiotics.Nature reviews. Microbiology · 2026
    Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sebastian Walesch *Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Saarbrücken, Germany.ORCID 0000-0002-1101-0939
Joy Birkelbach *Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Saarbrücken, Germany.ORCID 0000-0001-6847-8033
Gwenaëlle JézéquelHelmholtz Institute for Pharmaceutical Research Saarland (HIPS), Saarbrücken, Germany.ORCID 0000-0001-8945-8680
F P Jake HaecklHelmholtz Institute for Pharmaceutical Research Saarland (HIPS), Saarbrücken, Germany.ORCID 0000-0002-2776-5957
Julian D HegemannHelmholtz Institute for Pharmaceutical Research Saarland (HIPS), Saarbrücken, Germany.ORCID 0000-0002-3859-8744
Thomas HesterkampHelmholtz Centre for Infection research (HZI), Braunschweig, Germany.ORCID 0000-0002-2539-9068
Anna K H HirschHelmholtz Institute for Pharmaceutical Research Saarland (HIPS), Saarbrücken, Germany.ORCID 0000-0001-8734-4663
Peter HammannHelmholtz Institute for Pharmaceutical Research Saarland (HIPS), Saarbrücken, Germany.
Rolf MüllerHelmholtz Institute for Pharmaceutical Research Saarland (HIPS), Saarbrücken, Germany.ORCID 0000-0002-1042-5665

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibacterial resistance is one of the greatest threats to human health. The development of new therapeutics against bacterial pathogens has slowed drastically since the approvals of the first antibiotics in the early and mid-20

Indexed as

Biological ProductsDrug DiscoveryAnti-Bacterial AgentsBacteriaDrug Resistance, MicrobialHumansAnti-Bacterial AgentsBiological Productsantibacterial pipelineantibioticsantimicrobial resistanceinnovationpreclinical and clinical pipeline

Identifiers

PMID36533629
PMCPMC9827564

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.