Evidence map›Paper›PMID 36533622›Full record

ArticleJournal of the American Heart Association2022

Endovascular Treatment for Minor Acute Ischemic Strokes With Large Vessel Occlusion.

Rui Xue, Wansi Zhong, Ying Zhou, Yaode He, Shenqiang Yan, Zhicai Chen, Jianan Wang, Xiaoxian Gong, Min Lou

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Medium vessel occlusions in the drip-and-ship model: Clinical vs. hub CTP-supported decision making.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  4. Article
  5. Article
  6. IV thrombolysis plus thrombectomy versus IV thrombolysis alone for minor stroke with anterior circulation large vessel occlusion from the IRETAS and Italian SITS-ISTR cohorts.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023
    Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Rui XueDepartment of Neurology The Second Affiliated Hospital of Zhejiang University, School of Medicine Hangzhou China.ORCID 0000-0003-2582-2249
Wansi ZhongDepartment of Neurology The Second Affiliated Hospital of Zhejiang University, School of Medicine Hangzhou China.
Ying ZhouDepartment of Neurology The Second Affiliated Hospital of Zhejiang University, School of Medicine Hangzhou China.
Yaode HeDepartment of Neurology The Second Affiliated Hospital of Zhejiang University, School of Medicine Hangzhou China.ORCID 0000-0003-3616-6769
Shenqiang YanDepartment of Neurology The Second Affiliated Hospital of Zhejiang University, School of Medicine Hangzhou China.ORCID 0000-0001-6425-0672
Zhicai ChenDepartment of Neurology The Second Affiliated Hospital of Zhejiang University, School of Medicine Hangzhou China.
Jianan WangDepartment of Neurology The Second Affiliated Hospital of Zhejiang University, School of Medicine Hangzhou China.
Xiaoxian GongDepartment of Neurology The Second Affiliated Hospital of Zhejiang University, School of Medicine Hangzhou China.
Min LouDepartment of Neurology The Second Affiliated Hospital of Zhejiang University, School of Medicine Hangzhou China.ORCID 0000-0002-6627-064X
Second Affiliated Hospital of Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background It remains uncertain whether patients with minor acute ischemic stroke with large vessel occlusion benefit from endovascular treatment (EVT). We aim to evaluate the outcomes of EVT in minor acute ischemic stroke with anterior circulation large vessel occlusion. Methods and Results Based on a nationwide prospective stroke registry, patients with minor acute ischemic stroke with anterior circulation large vessel occlusion within 24 hours of onset were divided into groups receiving standard medical treatment plus EVT or standard medical treatment alone. Primary outcome was excellent functional outcome defined as modified Rankin Scale score 0 to 1 at 90 days. In addition, a multivariable logistic regression model was used to analyze the effect of EVT guided by perfusion imaging. A total of 572 patients with median age 68 years (interquartile range=60-77) and median National Institutes of Health Stroke score 3 (interquartile range =2-4) were identified and 123 patients were treated with standard medical treatment plus EVT. EVT was not associated with excellent functional outcome (unadjusted odds ratio [OR], 0.771 [95% CI, 0.516-1.151]; adjusted OR, 0.793 [95% CI, 0.515-1.219];

Indexed as

Brain IschemiaEndovascular ProceduresIschemic StrokeStrokeAgedHumansThrombectomyTreatment Outcomeendovascular treatmentlarge vessel occlusionminor acute ischemic strokeperfusion imaging

Identifiers

PMID36533622
PMCPMC9798802
OpenAlexW4312094830

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.