Evidence map›Paper›PMID 36533236›Full record

ArticleFrontiers in pediatrics2022

Splenic rupture and fungal endocarditis in a pediatric patient with invasive fusariosis after allogeneic hematopoietic stem cell transplantation for aplastic anemia: A case report.

Maurice Hannemann, Dunja Wilmes, Frank Dombrowski, Jürgen Löffler, Alexander Kaminski, Astrid Hummel, Lena Ulm, Jürgen Bohnert, Volker Rickerts, Jan Springer and 2 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Maurice HannemannDepartment of Pediatric Hematology and Oncology, University Medicine Greifswald, Greifswald, Germany.
Dunja WilmesDivision for Mycotic and Parasitic Agents and Mycobacteria, Robert Koch Institute, Berlin, Germany.
Frank DombrowskiInstitute of Pathology, University Medicine Greifswald, Greifswald, Germany.
Jürgen LöfflerDepartment of Internal Medicine II, University Hospital Würzburg, Würzburg, Germany.
Alexander KaminskiDepartment for Heart and Vascular Surgery, Klinikum Karlsburg, Karlsburg, Germany.
Astrid HummelDepartment of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany.
Lena UlmInstitute of Microbiology, University Medicine Greifswald, Greifswald, Germany.
Jürgen BohnertInstitute of Microbiology, University Medicine Greifswald, Greifswald, Germany.
Volker RickertsDivision for Mycotic and Parasitic Agents and Mycobacteria, Robert Koch Institute, Berlin, Germany.
Jan SpringerDepartment of Internal Medicine II, University Hospital Würzburg, Würzburg, Germany.
Holger N LodeDepartment of Pediatric Hematology and Oncology, University Medicine Greifswald, Greifswald, Germany.
Karoline EhlertDepartment of Pediatric Hematology and Oncology, University Medicine Greifswald, Greifswald, Germany.
Universitätsmedizin Greifswald · DERobert Koch Institute · DEUniversitätsklinikum Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Invasive mold infections are a well-known and life-threatening condition after allogeneic hematopoietic stem cell transplantation (HSCT). While Case presentation: Two weeks after allogeneic HSCT for severe aplastic anemia, a 16-year-old boy presented with painful, erythematous skin nodules affecting the entire integument. As disseminated mycosis was considered, treatment with liposomal amphotericin B and voriconazole (VCZ) was initiated. Invasive fusariosis was diagnosed after histological and previously unpublished polymerase chain reaction-based examination of skin biopsies. Microbiological tests revealed Conclusion: Invasive fusariosis in immunocompromised patients is a life-threatening condition. Despite antimycotic treatment adapted to antifungal susceptibility testing, the patient reported here developed uncommon manifestations such as splenic rupture and fungal endocarditis.

Indexed as

case reportendocarditisfusariumhematopoietic stem cell transplantationinvasive mold infectionsplenic rupture

Identifiers

PMID36533236
PMCPMC9755516
OpenAlexW4311093572

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.