Evidence map›Paper›PMID 36533163›Full record

ArticleBiotechnology reports (Amsterdam, Netherlands)2023

Immunogenicity and efficacy of recombinant subunit SARS-CoV-2 vaccine candidate in the Syrian hamster model.

Balamurugan Shanmugaraj, Narach Khorattanakulchai, Weena Paungpin, Yada Akkhawattanangkul, Suwimon Manopwisedjaroen, Arunee Thitithanyanont, Waranyoo Phoolcharoen

Abstract read
In one paragraph

Article in Biotechnology reports (Amsterdam, Netherlands), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Green Biologics: Harnessing the Power of Plants to Produce Pharmaceuticals.International journal of molecular sciences · 2023
    Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Balamurugan ShanmugarajBaiya Phytopharm Co., Ltd, Bangkok, 10330, Thailand.
Narach KhorattanakulchaiCenter of Excellence in Plant-produced Pharmaceuticals, Chulalongkorn University, Bangkok, 10330, Thailand.
Weena PaungpinFaculty of Veterinary Science, Mahidol University, Nakhon Pathom 73170, Thailand.
Yada AkkhawattanangkulFaculty of Veterinary Science, Mahidol University, Nakhon Pathom 73170, Thailand.
Suwimon ManopwisedjaroenDepartment of Microbiology, Faculty of Science, Mahidol University, Bangkok 10400, Thailand.
Arunee ThitithanyanontDepartment of Microbiology, Faculty of Science, Mahidol University, Bangkok 10400, Thailand.
Waranyoo PhoolcharoenCenter of Excellence in Plant-produced Pharmaceuticals, Chulalongkorn University, Bangkok, 10330, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SARS-CoV-2 causes devastating impact on the human population and has become a major public health concern. The frequent emergence of SARS-CoV-2 variants of concern urges the development of safe and efficacious vaccine against SARS-CoV-2 variants. We developed a candidate vaccine Baiya SARS-CoV-2 Vax 1, based on SARS-CoV-2 receptor-binding domain (RBD) by fusing with the Fc region of human IgG. The RBD-Fc fusion was produced in

Indexed as

COVID-19Plant-produced subunit vaccineProtective immunity, Hamster challengeReceptor binding domainSARS-CoV-2

Identifiers

PMID36533163
PMCPMC9744481

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.