Evidence map›Paper›PMID 36533152›Full record

ArticleVirus evolution2022

High genetic stability of co-circulating human adenovirus type 31 lineages over 59 years.

Jasper Götting, Claas Baier, Victoria Panagiota, Britta Maecker-Kolhoff, Akshay Dhingra, Albert Heim

Open access · goldAbstract read
In one paragraph

Article in Virus evolution, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jasper GöttingInstitute of Virology, Hannover Medical School, Carl-Neuberg-Str. 1, Hannover 30625, Germany.ORCID https://orcid.org/0000-0002-3891-5746
Claas BaierInstitute for Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Carl-Neuberg-Str. 1, Hannover 30625, Germany.
Victoria PanagiotaDepartment of Hematology, Hemostaseology, Oncology and Stem Cell Transplantation, Hannover Medical School, Carl-Neuberg-Str. 1, Hannover 30625, Germany.
Britta Maecker-KolhoffDepartment of Paediatric Haematology and Oncology, Hannover Medical School, Carl-Neuberg-Str. 1, Hannover 30625, Germany.
Akshay DhingraInstitute of Virology, Hannover Medical School, Carl-Neuberg-Str. 1, Hannover 30625, Germany.
Albert HeimInstitute of Virology, Hannover Medical School, Carl-Neuberg-Str. 1, Hannover 30625, Germany.ORCID https://orcid.org/0000-0002-9447-1561
Medizinische Hochschule Hannover · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Type 31 of human adenovirus species A (HAdV-A31) is a significant pathogen primarily associated with diarrhoea in children but also with life-threatening disseminated disease in allogeneic haematopoietic stem cell transplant (HSCT) recipients. Nosocomial outbreaks of HAdV-A31 have been frequently described. However, the evolution of HAdV-A31 has not been studied in detail. The evolution of other HAdV types is driven either by intertypic recombination, where different types exchange genome regions, or by immune escape selection of neutralisation determinants. Complete genomic HAdV-A31 sequences from sixty diagnostic specimens of the past 18 years (2003-21) were generated, including fourteen specimens of a presumed outbreak on two HSCT wards. Additionally, twenty-three complete genomes from GenBank were added to our phylogenetic analysis as well as

Indexed as

Adenoviruscomplete genomic sequencingDNA virusgenomicsmolecular epidemiologymolecular evolutionnosocomial

Identifiers

PMID36533152
PMCPMC9748976
OpenAlexW4289730883

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.