Evidence map›Paper›PMID 36532891›Full record

ArticleJournal of molecular structure2022

Novel indolo [3,2-c]isoquinoline-5-one-6-yl [1,2,4]triazolo [3,4-b] [1,3,4]thiadiazole analogues: Design, synthesis, anticancer activity, docking with SARS-CoV-2 Omicron protease and MESP/TD-DFT approaches.

Vaijinath A Verma, Anand R Saundane, Raju Shamrao, Rajkumar S Meti, Venkat M Shinde

Open access · greenAbstract read
In one paragraph

Article in Journal of molecular structure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Vaijinath A VermaDepartment of Chemistry, Sri Prabhu Arts, Science and J. M. Bohra Commerce Degree College, Shorapur-585 224, Yadgir, Karnataka, India.
Anand R SaundaneDepartment of P.G. Studies and Research in Chemistry, Gulbarga University, Kalaburagi, 585106, Karnataka, India.
Raju ShamraoDepartment of Chemistry, Government First Grade College, Shahapur-585 223, Yadgir, Karnataka, India.
Rajkumar S MetiDepartment of Biochemistry, Mangalore University, P.G. Centre Chikka Aluvara, 571234, Karnataka, India.
Venkat M ShindeDepartment of Botany, Gulbarga University, Kalaburagi, Karnataka, 585 106, India.
Gulbarga University · INMangalore University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Indoloisoquinoline derivatives are associated with varieties of biological and pharmacological properties. Therefore, we herein reported the synthesis of novel series of indolo [3,2-c]isoquinoline incorporated with [1,2,4]triazolo [3,4-b] [1,3,4]thiadiazole moieties. Spectroscopic methods were used to determine the chemical structures of these molecules. Whereas, the B3LYP functional with the def2-SVP basis set were used to improve TD-DFT geometries and solvent effects. Investigations, which are directly connected to the optical spectra (absorption and emission) of molecules. These findings reveals that the compound

Indexed as

Indolo [3,2-c]isoquinolineMESP: anticancerMolecular dockingSARS-CoV-2 omicron proteaseTDDFT

Identifiers

PMID36532891
PMCPMC9749848
OpenAlexW4224434472

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.