Evidence map›Paper›PMID 36532868›Full record

ArticleFrontiers in computational neuroscience2022

Quasicriticality explains variability of human neural dynamics across life span.

Leandro J Fosque, Abolfazl Alipour, Marzieh Zare, Rashid V Williams-García, John M Beggs, Gerardo Ortiz

Abstract read
In one paragraph

Article in Frontiers in computational neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Power Laws in Empirical Eigenvalue Spectra.Entropy (Basel, Switzerland) · 2026
    Article
  3. Criticality and increased intrinsic neural timescales in stroke.NPJ systems biology and applications · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Critical-like Brain Dynamics in a Continuum from Second- to First-Order Phase Transition.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Leandro J FosqueDepartment of Physics, Indiana University, Bloomington, IN, United States.
Abolfazl AlipourDepartment of Psychological and Brain Sciences, Indiana University, Bloomington, IN, United States.
Marzieh ZareAI Practice, CGI, Montreal, QC, Canada.
Rashid V Williams-GarcíaDépartement de Physique, Institut Denis Poisson (UMR7013), Tours, France.
John M BeggsDepartment of Physics, Indiana University, Bloomington, IN, United States.
Gerardo OrtizDepartment of Physics, Indiana University, Bloomington, IN, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aging impacts the brain's structural and functional organization and over time leads to various disorders, such as Alzheimer's disease and cognitive impairment. The process also impacts sensory function, bringing about a general slowing in various perceptual and cognitive functions. Here, we analyze the Cambridge Centre for Ageing and Neuroscience (Cam-CAN) resting-state magnetoencephalography (MEG) dataset-the largest aging cohort available-in light of the quasicriticality framework, a novel organizing principle for brain functionality which relates information processing and scaling properties of brain activity to brain connectivity and stimulus. Examination of the data using this framework reveals interesting correlations with age and gender of test subjects. Using simulated data as verification, our results suggest a link between changes to brain connectivity due to aging and increased dynamical fluctuations of neuronal firing rates. Our findings suggest a platform to develop biomarkers of neurological health.

Indexed as

agingCam-CAN datasethealthy humanmagnetoencephalography (MEG)neuronal avalanchesquasicriticality

Identifiers

PMID36532868
PMCPMC9747757

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.