Evidence map›Paper›PMID 36532776›Full record

ReviewFrontiers in pharmacology2022

Selective serotonin reuptake inhibitors: New hope in the fight against COVID-19.

Mahsa Asadi Anar, Elaheh Foroughi, Elika Sohrabi, Samira Peiravi, Yasaman Tavakoli, Mozhgan Kameli Khouzani, Parisa Behshood, Melika Shamshiri, Arezoo Faridzadeh, Kimia Keylani and 7 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 9 institutions in 2 countries.

Mahsa Asadi AnarStudent Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Elaheh ForoughiSchool of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Elika SohrabiDepartment of Medicine, Islamic Azad University of Medical Sciences, Tehran, Iran.
Samira PeiraviDepartment of Emergency Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Yasaman TavakoliDepartment of Medicine, Mazandaran University of Medical Sciences, Sari, Mazandaran, Iran.
Mozhgan Kameli KhouzaniDepartment of Biology, Science, and Research Branch, Islamic Azad University, Tehran, Iran.
Parisa BehshoodDepartment of Microbiology, Young Researchers and Elite Club, Islamic Azad University, Shahrekord, Iran.
Melika ShamshiriSchool of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Arezoo FaridzadehDepartment of Immunology and Allergy, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Kimia KeylaniSchool of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Seyedeh Faride LangariDepartment of Ophthalmology, Labbafinejad Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Akram AnsariShantou University Medical College, Shantou, Guangdong, China.
Amirmohammad KhalajiSchool of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Setareh GarousiFaculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mehran MottahediFaculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Sara HonariFaculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Niloofar DeraviStudent Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mashhad University of Medical Sciences · IRShahid Beheshti University of Medical Sciences · IRIsfahan University of Medical Sciences · IRIslamic Azad University Medical Branch of Tehran · IRIslamic Azad University of Shahrekord · IRKermanshah University of Medical Sciences · IRMazandaran University of Medical Sciences · IRShantou University Medical College · CNTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The emerging COVID-19 pandemic led to a dramatic increase in global mortality and morbidity rates. As in most infections, fatal complications of coronavirus affliction are triggered by an untrammeled host inflammatory response. Cytokine storms created by high levels of interleukin and other cytokines elucidate the pathology of severe COVID-19. In this respect, repurposing drugs that are already available and might exhibit anti-inflammatory effects have received significant attention. With the

Indexed as

antidepressantscoronavirusCOVID-19fluoxetine (Prozac)fluvoxamine (Luvox)SARS-CoV-2sertraline (Zoloft)SSRIs drugs

Identifiers

PMID36532776
PMCPMC9748354
OpenAlexW4310992590

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.