ArticleFrontiers in microbiology2022
Epidemiological investigation and genetic evolutionary analysis of PRRSV-1 on a pig farm in China.
Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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33 citing papers in PubMed, 44 citations in OpenAlex.
- Characterization and pathogenicity of single-farm-isolated PRRSV 1 and PRRSV 2 strain in China.Virulence · 2026Article
- Integration of ATAC-seq and RNA-seq analysis identifies host genes related with PRRSV infection.Veterinary research · 2026Article
- Genetic evolutionary and pathogenicity analyses of a novel porcine reproductive and respiratory syndrome virus 1 strain SC202404 that emerged in Southwestern China.BMC veterinary research · 2026Article
- Emergence and Pathogenicity of a Novel PRRSV-1 Strain GD18-2 in Southern China.Animals : an open access journal from MDPI · 2026Article
- Development of a novel duplex crystal digital PCR for the detection of PRRSV-1 and PRRSV-2.Frontiers in cellular and infection microbiology · 2026Article
- Comparative epidemiology and preparedness for African swine fever and porcine reproductive and respiratory syndrome in four major Asian swine industries.Frontiers in veterinary science · 2026Review
- Article
- Development of GFP-expressing infectious clones for PRRSV using TAR cloning for antiviral drug screening.Npj viruses · 2025Article
- Genetic variation in NSP4 of type 1 porcine reproductive and respiratory syndrome virus in China.BMC veterinary research · 2025Article
- Article
- Reproductive Failure in Smallholder Pig Farms in East and Southeast Asia: A Systematic Review.Animals : an open access journal from MDPI · 2025Review
- Isolation and Genomic Characterization of a Novel Porcine Reproductive and Respiratory Syndrome Virus 1 from Severely Diseased Piglets in China in 2024.Veterinary sciences · 2025Article
- Epidemiology and Pathogenicity Analysis Based on Partial Recombinant PRRSV Strains in China.Transboundary and emerging diseases · 2025Article
- Development of SYBR green I-based real-time qPCR differential diagnosis assays for porcine reproductive and respiratory syndrome virus typing in Guangdong province.Frontiers in veterinary science · 2025Article
- Whole-Genomic Characterization of Two Different PRRSV-1 Strains Isolated From a Single Pig.Transboundary and emerging diseases · 2025Article
- Epidemiology and genetic characterization of porcine reproductive and respiratory syndrome virus in Fujian Province, China, from 2023 to 2024.Frontiers in veterinary science · 2025Article
- Isolation and pathogenicity of the novel porcine reproductive and respiratory syndrome virus 1 strain ZJ01 in South China.Frontiers in cellular and infection microbiology · 2025Article
- Genetic evolution, epidemic trends, and recombination dynamics of PRRSV-1 in China.Frontiers in veterinary science · 2025Article
- Prevalence and genetic diversity ofFrontiers in veterinary science · 2025Article
- A chimeric strain of porcine reproductive and respiratory syndrome virus 2 derived from HP-PRRSV and NADC30-like PRRSV confers cross-protection against both strains.Veterinary research · 2024Article
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Authors and funding
18 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Porcine reproductive and respiratory syndrome virus (PRRSV) has brought serious economic losses to pig industry. PRRSV-1 have existed in China for more than 25 years. The prevalence and features of PRRSV-1 on Chinese farms are unclear. We continuously monitored PRRSV in a pig farm with strict biosafety measures in Henan Province, China, in 2020. The results showed that multiple types of PRRSV coexisted on this single pig farm. PRRSV-1 was one of the main circulating strains on the farm and was responsible for infections throughout nearly the entire epidemic cycle. Phylogenetic analysis showed that PRRSV-1 isolates from this pig farm formed an independent branch, with all isolates belonging to BJEU06-1-like PRRSV. The analysis of selection pressure on ORF5 on this branch identified 5 amino acids as positive selection sites, indicating that PRRSV-1 had undergone adaptive evolution on this farm. According to the analysis of ORF5 of PRRSV-1 on this farm, the evolutionary rate of the BJEU06-1-like branch was estimated to be 1.01 × 10
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