ArticleFrontiers in microbiology2022
Rumen-protected glucose supplementation alters fecal microbiota and its metabolic profiles in early lactation dairy cows.
Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 13 citations in OpenAlex.
- Effects of rumen-protected glucose supplementation strategies on growth performance, colonic fermentation, and meat quality in Simmental beef cattle.Animal bioscience · 2026Article
- Effects of bypass sugar supplementation from the close-up period through 5 days after calving on milk production, blood profiles, and health conditions in dairy cows.Animal bioscience · 2026Article
- Rumen-Protected Glucose Supplementation Enhances Yak Calf Growth Through Gut Microbiota-Metabolic Interactions.Animals : an open access journal from MDPI · 2026Article
- Current Understanding of Bovine Ketosis: From Molecular Basis to Farm-Level Management.Animals : an open access journal from MDPI · 2025Review
- Metabolomic signatures reveal mechanisms of rumen-protected glutathione in mitigating oxidative stress and regulating inflammatory networks in transition dairy cows.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2025Article
- Dietary D-Ribose Supplementation in Sheep: Implications on Rumen, Fecal Microbiota, and Metabolic Function.Microorganisms · 2025Article
- Effects of Dietary Rumen-Protected Glucose and Rumen-Protected Taurine Levels on Growth Performance, Serum Biochemical Indicators, and Liver Health in Yaks.Animals : an open access journal from MDPI · 2025Article
- Aloe arborescens supplementation in drying-off dairy cows: influence on rumen, rectum and milk microbiomes.Animal microbiome · 2024Article
- Analysis of the microbial diversity in takin (Frontiers in microbiology · 2023Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Negative energy balance (NEB) is the pathological basis of metabolic disorders in early lactation dairy cows. Rumen-protected glucose (RPG) is a feed additive to relieve NEB of cows in early lactation. The aims of the current study were to evaluate the impact of different doses of RPG supply on fecal microbiota and metabolome in early lactation dairy cows, and their correlation with each other. Methods: A total of 24 multiparous Holstein dairy cows in early lactation were randomly assigned to one of four treatments for the first 35 days of the early lactation period, as follows: control group, a basal diet without RPG (CON); low RPG, a basal diet plus 200 g/d RPG (LRPG); medium RPG, a basal diet plus 350 g/d RPG (MRPG); or HRPG, high RPG, a basal diet plus 500 g/d RPG (HRPG). After 35 days, fecal samples were obtained from cows in all groups individually and using 16S rRNA gene sequencing to evaluate their microbiotas, while their metabolites were evaluated through metabolomics. Results: As expected, Conclusion: In conclusion, RPG supplementation can affect the fecal microbial components and microbial metabolism, and 350 g RPG might be the ideal dose as a daily supplement.
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