Evidence map›Paper›PMID 36532196›Full record

ReviewFrontiers in psychiatry2022

Lower-dose psycholytic therapy - A neglected approach.

Torsten Passie, Jeffrey Guss, Rainer Krähenmann

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Frontiers in psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06798636 (Investigating the Effects of a Psychedelic-augmented Mental Imagery-based Intervention for Young People With Self-harm Behaviour), which is not on this map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
11.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06798636 early_phase1recruitingnot on this mapstarted 2025, after this paper: background citation

Investigating the Effects of a Psychedelic-augmented Mental Imagery-based Intervention for Young People With Self-harm Behaviour: an Experimental Medicine Study

TypeinterventionalSponsorImperial College LondonRan2025 to 2026Enrolled30ConditionsSelf HarmArmsPsilocybin 5 mg with cognitive behavioural therapy intervention, Placebo with cognitive behavioural therapy intervention
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

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  17. Use of psychedelic treatments in psychiatric clinical practice: an EPA policy paper.European psychiatry : the journal of the Association of European Psychiatrists · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 4 countries.

Torsten PassieHannover Medical School, Hannover, Germany.
Jeffrey GussGrossman School of Medicine, New York University, New York, NY, United States.
Rainer KrähenmannPsychiatric Services Thurgau, Münsterlingen, Switzerland.
Goethe University Frankfurt · DENew York University · USParacelsus Medical University · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lysergic acid diethylamide (LSD) and similar psychoactive drugs have been used in psychotherapy since 1949, when the first clinical study with lower-dose LSD showed therapeutically relevant effects. This caused an intense interest among psychotherapists and researchers, alike, on an international scale. In 1960, the use of serial lower-dose LSD/psilocybin sessions in a psychoanalytical framework, which was dominant at the time, was named

Indexed as

hallucinogenslower-dose LSD therapyLSDMDMAmystical experiencepsilocybinpsychoanalysispsycholytic therapy

Identifiers

PMID36532196
PMCPMC9755513
OpenAlexW4311093363

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.