Evidence map›Paper›PMID 36532052›Full record

ArticleFrontiers in immunology2022

Case report: Hemophagocytic lymphohistiocytosis in a child with primary immunodeficiency infected with

Huimin Yan, Yunjun Mo, Shilin Liu, Xiaojuan Luo, Lianlian Liu, Lintao Zhou, Xiuming Zhang, Yunsheng Chen, Ke Cao

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
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  5. [A case of hepatitis-associated aplastic anemia complicated by hemophagocytic lymphohistiocytosis and literature review].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2025
    Review
  6. Review
  7. Review
  8. Article
  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Huimin YanClinical Laboratory, Shenzhen Children's Hospital, Shenzhen, Guangdong, China.
Yunjun MoMedical Laboratory, Shenzhen Luohu People's Hospital, Shenzhen, Guangdong, China.
Shilin LiuDivision of Hematology and Oncology, Shenzhen Children's Hospital, Shenzhen, Guangdong, China.
Xiaojuan LuoClinical Laboratory, Shenzhen Children's Hospital, Shenzhen, Guangdong, China.
Lianlian LiuClinical Laboratory, Shenzhen Children's Hospital, Shenzhen, Guangdong, China.
Lintao ZhouClinical Laboratory, Shenzhen Children's Hospital, Shenzhen, Guangdong, China.
Xiuming ZhangMedical Laboratory, Shenzhen Luohu People's Hospital, Shenzhen, Guangdong, China.
Yunsheng ChenClinical Laboratory, Shenzhen Children's Hospital, Shenzhen, Guangdong, China.
Ke CaoClinical Laboratory, Shenzhen Children's Hospital, Shenzhen, Guangdong, China.
Shenzhen Children's Hospital · CNShenzhen Luohu People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening immune-mediated disease that affects patients with known genetic defects and is increasingly found among those with autoimmune diseases and persistent infections.

Indexed as

Lymphohistiocytosis, HemophagocyticTalaromycesChildHumansImmunocompromised HostMutationCARD9CD40LGhemophagocytic lymphohistiocytosisimmunodeficiency diseaseTalaromyces marneffei

Identifiers

PMID36532052
PMCPMC9755863
OpenAlexW4311192249

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.