ReviewFrontiers in cell and developmental biology2022
Squeezing the eggs to grow: The mechanobiology of mammalian folliculogenesis.
Review in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
25 citing papers in PubMed, 32 citations in OpenAlex.
- The Fibro-Inflammatory Ovary: Stromal Fibrosis, Extracellular Matrix Remodeling, and Mechanotransduction in Female Infertility.Current issues in molecular biology · 2026Review
- Mechanics of compression-driven morphogenesis.Development (Cambridge, England) · 2026Review
- Three-dimensional mapping of intact ovaries reveals the aging dynamics of the ovarian reserve.Nature aging · 2026Article
- Developmental and functional landscape of theca cells in ovarian biology.Biological research · 2026Review
- Knockout of filamin A in KGN granulosa tumor cells impairs proliferation, cell cycle progression, migration, and cytoskeletal organization under mechanical stress.Biological research · 2026Article
- The Nemp1-Nesprin complex mediates cellular responses to matrix mechanics.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Forceful Beginnings: Mechanotransduction and Mechanosensation at the Meiotic Cell Nucleus During Gamete Development.Results and problems in cell differentiation · 2026Review
- Characterization of isolated late preantral and early antral equine ovarian follicles.Reproduction & fertility · 2026Article
- Negative impacts of ovarian endometrioma on preantral follicle development: implications for endometriosis-related infertility.Frontiers in endocrinology · 2026Article
- Comparison of the biomechanical characteristics of human ovarian tissue after vitrification versus slow freezing.JBRA assisted reproduction · 2025Article
- Overexpressed miR-135b in the ovaries of PCOS promotes granulosa cell proliferation by inhibiting Hippo signaling pathway.Journal of assisted reproduction and genetics · 2025Article
- Three-dimensional quantitative micro-elastography reveals alterations in spatial elasticity patterns in murine ovaries during ageing.Communications biology · 2025Article
- Biophysical, cellular, and mouse model approaches to investigate the mechanical regulation of folliculogenesis.Seminars in cell & developmental biology · 2025Review
- Transcriptome Sequencing and Differential Analysis of Ovaries Across Diverse States (Follicular and Non-Follicular Phases).Animals : an open access journal from MDPI · 2025Article
- Extracellular matrix dysregulation in PCOS: pathogenesis, therapeutic strategies, and innovative technologies.Journal of biological engineering · 2025Review
- Reproductive seasonality influences follicle dynamics and the ovarian extracellular matrix structural properties in ewes.Reproduction (Cambridge, England) · 2025Article
- Autonomous follicle quality control mechanisms: innate immune signaling capabilities of granulosa cells.Reproduction (Cambridge, England) · 2025Review
- Primordial Follicle Response to Two Methods of Ovarian Cortex Retrieval and Vitrification: A Pilot Study.Cureus · 2025Article
- Advances in ovarian follicle culture systems: exploring the interplay between cells, matrix, and ovarian architecture.Animal reproduction · 2025Article
- Novel imaging and biophysical approaches to study tissue hydraulics in mammalian folliculogenesis.Biophysical reviews · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The formation of functional eggs (oocyte) in ovarian follicles is arguably one of the most important events in early mammalian development since the oocytes provide the bulk genetic and cytoplasmic materials for successful reproduction. While past studies have identified many genes that are critical to normal ovarian development and function, recent studies have highlighted the role of mechanical force in shaping folliculogenesis. In this review, we discuss the underlying mechanobiological principles and the force-generating cellular structures and extracellular matrix that control the various stages of follicle development. We also highlight emerging techniques that allow for the quantification of mechanical interactions and follicular dynamics during development, and propose new directions for future studies in the field. We hope this review will provide a timely and useful framework for future understanding of mechano-signalling pathways in reproductive biology and diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.