Evidence map›Paper›PMID 36531928›Full record

ArticleThe Lancet regional health. Southeast Asia2023

An observational multi-centric COVID-19 sequelae study among health care workers.

Ajay Kumar Shukla, Shubham Atal, Aditya Banerjee, Ratinder Jhaj, Sadasivam Balakrishnan, Preeta Kaur Chugh, Denis Xavier, Atiya Faruqui, Aakanksha Singh, Ramasamy Raveendran and 21 more

Open access · diamondAbstract read
In one paragraph

Article in The Lancet regional health. Southeast Asia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 6 pooled it
4.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 6 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Prevalence and symptoms of Long Covid-19 in the workplace.Occupational medicine (Oxford, England) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors at 9 institutions in 1 country.

Ajay Kumar ShuklaDepartment of Pharmacology, All India Institute of Medical Sciences, Saket Nagar, Bhopal, Madhya Pradesh, 462020, India.
Shubham AtalDepartment of Pharmacology, All India Institute of Medical Sciences, Saket Nagar, Bhopal, Madhya Pradesh, 462020, India.
Aditya BanerjeeDepartment of Pharmacology, All India Institute of Medical Sciences, Saket Nagar, Bhopal, Madhya Pradesh, 462020, India.
Ratinder JhajDepartment of Pharmacology, All India Institute of Medical Sciences, Saket Nagar, Bhopal, Madhya Pradesh, 462020, India.
Sadasivam BalakrishnanDepartment of Pharmacology, All India Institute of Medical Sciences, Saket Nagar, Bhopal, Madhya Pradesh, 462020, India.
Preeta Kaur ChughDepartment of Pharmacology, Vardhman Mahavir Medical College & Safdarjung Hospital, Near AIIMS Hospital, Ansari Nagar West, New Delhi, 110029, India.
Denis XavierDepartment of Pharmacology, St John's Medical College Sarjapur - Marathahalli Rd, Beside Bank of Baroda, John Nagar, Koramangala, Bengaluru, Karnataka, 560034, India.
Atiya FaruquiDepartment of Pharmacology, St John's Medical College Sarjapur - Marathahalli Rd, Beside Bank of Baroda, John Nagar, Koramangala, Bengaluru, Karnataka, 560034, India.
Aakanksha SinghDepartment of Pharmacology, St John's Medical College Sarjapur - Marathahalli Rd, Beside Bank of Baroda, John Nagar, Koramangala, Bengaluru, Karnataka, 560034, India.
Ramasamy RaveendranDepartment of Pharmacology, Jawaharlal Institute of Postgraduate Medical Education & Research, JIPMER Campus Rd, Gorimedu, Priyadarshini Nagar, Puducherry, 605006, India.
Jayanthi MathaiyanDepartment of Pharmacology, Jawaharlal Institute of Postgraduate Medical Education & Research, JIPMER Campus Rd, Gorimedu, Priyadarshini Nagar, Puducherry, 605006, India.
Jeevitha GauthamanDepartment of Pharmacology, Jawaharlal Institute of Postgraduate Medical Education & Research, JIPMER Campus Rd, Gorimedu, Priyadarshini Nagar, Puducherry, 605006, India.
Urwashi I ParmarDepartment of Pharmacology & Therapeutics, Seth G. S. Medical College & K. E. M. Hospital, Acharya Donde Marg, Parel East, Parel, Mumbai, Maharashtra, 400012, India.
Raakhi K TripathiDepartment of Pharmacology & Therapeutics, Seth G. S. Medical College & K. E. M. Hospital, Acharya Donde Marg, Parel East, Parel, Mumbai, Maharashtra, 400012, India.
Sandhya K KamatDepartment of Pharmacology & Therapeutics, Seth G. S. Medical College & K. E. M. Hospital, Acharya Donde Marg, Parel East, Parel, Mumbai, Maharashtra, 400012, India.
Niyati TrivediDepartment of Pharmacology, Medical College, Baroda, Vinoba Bhave Rd, Anandpura, Vadodara, Gujarat, 390001, India.
Prashant ShahDepartment of Pharmacology, Medical College, Baroda, Vinoba Bhave Rd, Anandpura, Vadodara, Gujarat, 390001, India.
Janki ChauhanDepartment of Pharmacology, Medical College, Baroda, Vinoba Bhave Rd, Anandpura, Vadodara, Gujarat, 390001, India.
Harihar DikshitDepartment of Pharmacology, Indira Gandhi Institute of Medical Sciences, Allahabad Bank, Bailey Rd, Sheikhpura, Patna, Bihar, 800014, India.
Hitesh MishraDepartment of Pharmacology, Indira Gandhi Institute of Medical Sciences, Allahabad Bank, Bailey Rd, Sheikhpura, Patna, Bihar, 800014, India.
Rajiv KumarDepartment of Pharmacology, Indira Gandhi Institute of Medical Sciences, Allahabad Bank, Bailey Rd, Sheikhpura, Patna, Bihar, 800014, India.
Dinesh Kumar BadyalDepartment of Pharmacology, Christian Medical College and Hospital, Brown Rd, CMC Campus, Ludhiana, Punjab, 141008, India.
Monika SharmaDepartment of Paediatrics, Christian Medical College and Hospital, Brown Rd, CMC Campus, Ludhiana, Punjab, 141008, India.
Mamta SinglaDepartment of Psychiatry, Christian Medical College and Hospital, Brown Rd, CMC Campus, Ludhiana, Punjab, 141008, India.
Bikash MedhiDepartment of Pharmacology, Postgraduate Institute of Medical Education and Research, Madhya Marg, Sector 12, Chandigarh, 160012, India.
Ajay PrakashDepartment of Pharmacology, Postgraduate Institute of Medical Education and Research, Madhya Marg, Sector 12, Chandigarh, 160012, India.
Rupa JoshiDepartment of Pharmacology, Postgraduate Institute of Medical Education and Research, Madhya Marg, Sector 12, Chandigarh, 160012, India.
Nabendu S ChatterjeeDept. of Health Research, Ministry of Health and Family Welfare, V. Ramalingaswami Bhawan, P.O. Box No. 4911. Ansari Nagar, New Delhi, 110029, India.
Jerin Jose CherianDept. of Health Research, Ministry of Health and Family Welfare, V. Ramalingaswami Bhawan, P.O. Box No. 4911. Ansari Nagar, New Delhi, 110029, India.
Ved Prakash KambojDept. of Health Research, Ministry of Health and Family Welfare, V. Ramalingaswami Bhawan, P.O. Box No. 4911. Ansari Nagar, New Delhi, 110029, India.
Nilima KshirsagarDept. of Health Research, Ministry of Health and Family Welfare, V. Ramalingaswami Bhawan, P.O. Box No. 4911. Ansari Nagar, New Delhi, 110029, India.
All India Institute of Medical Sciences Bhopal · INMinistry of Health and Family Welfare · INChristian Medical College, Vellore · INIndira Gandhi Institute of Medical Sciences · INJawaharlal Institute of Post Graduate Medical Education and Research · INKing Edward Memorial Hospital and Seth G.S. Medical College · INSir Sayajirao General Hospital Medical College · INPost Graduate Institute of Medical Education and Research · INVardhman Mahavir Medical College & Safdarjung Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: India has seen more than 43 million confirmed cases of COVID-19 as of April 2022, with a recovery rate of 98.8%, resulting in a large section of the population including the healthcare workers (HCWs), susceptible to develop post COVID sequelae. This study was carried out to assess the nature and prevalence of medical sequelae following COVID-19 infection, and risk factors, if any. Methods: This was an observational, multicenter cross-sectional study conducted at eight tertiary care centers. The consenting participants were HCWs between 12 and 52 weeks post discharge after COVID-19 infection. Data on demographics, medical history, clinical features of COVID-19 and various symptoms of COVID sequelae was collected through specific questionnaire. Finding: Mean age of the 679 eligible participants was 31.49 ± 9.54 years. The overall prevalence of COVID sequelae was 30.34%, with fatigue (11.5%) being the most common followed by insomnia (8.5%), difficulty in breathing during activity (6%) and pain in joints (5%). The odds of having any sequelae were significantly higher among participants who had moderate to severe COVID-19 (OR 6.51; 95% CI 3.46-12.23) and lower among males (OR 0.55; 95% CI 0.39-0.76). Besides these, other predictors for having sequelae were age (≥45 years), presence of any comorbidity (especially hypertension and asthma), category of HCW (non-doctors vs doctors) and hospitalisation due to COVID-19. Interpretation: Approximately one-third of the participants experienced COVID sequelae. Severity of COVID illness, female gender, advanced age, co-morbidity were significant risk factors for COVID sequelae. Funding: This work is a part of Indian Council for Medical Research (ICMR)- Rational Use of Medicines network. No additional financial support was received from ICMR to carry out the work, for study materials, medical writing, and APC.

Indexed as

ACE2, Angiotensin-converting enzyme 2AE, Adverse eventsBMI, Body mass indexCAD, Coronary artery diseaseCI, Confidence intervalCOVID-19COVID-19, Corona virus disease 2019COVID sequelaeCTRI, Clinical Trials Registry- IndiaDASS-21, Depression, Anxiety, and Stress Scale-21ENT, Ear, nose, and throatGERD, Gastroesophageal reflux diseaseHCQ, HydroxychloroquineHCW, Health care workerICMR, Indian council of medical researchICMR-RUMCLong COVIDMOHFW, Ministry of Health and Family Welfare, Govt. of IndiaNICE, National Institute for Health and Clinical ExcellenceOR, Odds ratioPCOS, Polycystic Ovarian DiseasePLOG, Polymerase gamma-related disordersp-value, Probability valueRHD, Rheumatic heart diseaseRUMC, Rational use of medicine centerSARS-CoV-2SARS-CoV-2, Severe Acute Respiratory Syndrome Coronavirus 2WHO, World Health Organization

Identifiers

PMID36531928
PMCPMC9744681
OpenAlexW4311230968

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.