Evidence map›Paper›PMID 36531841›Full record

ArticleThe Neurohospitalist2023

Unplanned Admissions, Emergency Department Visits, and Epilepsy After Critical Neurological Illness Requiring Prolonged Mechanical Ventilation in Children.

Matthew B Spear, Kristen Miller, Craig Press, Christopher Ruzas, Jaime LaVelle, Peter M Mourani, Tellen D Bennett, Aline B Maddux

Open access · greenAbstract read
In one paragraph

Article in The Neurohospitalist, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Matthew B SpearDepartment of Pediatrics, University of Texas at Austin Dell Medical School, Austin, TX, USA.
Kristen MillerDepartment of Pediatrics, University of Colorado School of Medicine, Aurora, CO, USA.
Craig PressDepartment of Pediatrics, Division of Neurology, University of Pennsylvania School of Medicine and Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Christopher RuzasDepartment of Pediatrics, Section of Critical Care Medicine, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO, USA.
Jaime LaVellePediatrics, Children's Hospital Colorado, Aurora, CO, USA.
Peter M MouraniDepartment of Pediatrics, Section of Critical Care, University of Arkansas for Medical Sciences and Arkansas Children's, Little Rock, AR, USA.
Tellen D BennettDepartment of Pediatrics, Section of Critical Care Medicine, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO, USA.
Aline B MadduxDepartment of Pediatrics, Section of Critical Care Medicine, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO, USA.ORCID https://orcid.org/0000-0002-0949-4284
Children's Hospital Colorado · USArkansas Children's Hospital · USChildren's Hospital of Philadelphia · USThe University of Texas at Austin · USUniversity of Colorado Denver · US

Funding

Functional Outcomes after Prolonged Mechanical Ventilation in ChildrenK23HD096018 · NICHD · UNIVERSITY OF COLORADO DENVER · PI MADDUX, ALINE BERNARD · 2019 to 2023
$807k
NICHD NIH HHS K23 HD096018
6 · The paper itself

Abstract

Background and Purpose: Long-term outcomes after pediatric neurocritical illness are poorly characterized. This study aims to characterize the frequency and risk factors for post-discharge unplanned health resource use in a pediatric neurocritical care population using insurance claims data. Methods: Retrospective cohort study evaluating children who survived a hospitalization for an acute neurologic illness or injury requiring mechanical ventilation for >72 hours and had insurance eligibility in Colorado's All Payers Claims database. Insurance claims identified unplanned readmissions and emergency department [ED] visits during the post-discharge year. For patients without pre-existing epilepsy/seizures, we evaluated for post-ICU epilepsy identified by claim(s) for a maintenance anti-seizure medication during months 6-12 post-discharge. Multivariable logistic regression identified factors associated with each outcome. Results: 101 children, median age 3.7 years (interquartile range (IQR) .4-11.9), admitted for trauma (57%), hypoxic-ischemic injury (17%) and seizures (15%). During the post-discharge year, 4 (4%) patients died, 26 (26%) were readmitted, and 48 (48%) had an ED visit. Having a pre-existing complex chronic condition was independently associated with readmission and emergency department visit. Admission for trauma was protective against readmission. Of those without pre-existing seizures (n = 86), 25 (29%) developed post-ICU epilepsy. Acute seizures during admission and prolonged ICU stays were independently associated with post-ICU epilepsy. Conclusions: Survivors of pediatric neurocritical illness are at risk of unplanned healthcare use and post-ICU epilepsy. Critical illness risk factors including prolonged ICU stay and acute seizures may identify cohorts for targeted follow up or interventions to prevent unplanned healthcare use and post-ICU epilepsy.

Indexed as

administrative claimsbrain injurieschildcritical care outcomeshealthcareintensive care unitspediatric

Identifiers

PMID36531841
PMCPMC9755613
OpenAlexW4303946192

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.